In a recent article, Nicholas A. Meanwell elaborated on the cutting-edge application of bioisosteres in Drug Discovery.

Inspired by this review, we have prepared a set of Building Blocks that share the most prominent carboxylic acid isosteres in marketed drugs. Among them are tetrazoles, acyl sulfonamides, hydroxamic acids, 3-hydroxy oxetanes, and several other acyclic and heterocyclic moieties mentioned in the article.

 

Discover Chemspace Carboxylic Acid Bioisosteres – a library of 380 in-stock compounds that share more than 15 isosteric types.

Drop us a line if you have any questions: info@chem-space.com

 

Chemspace | Carboxylic Acid Bioisosteres.  A library of 380 in-stock compounds that share more than 15 isosteric types.