The third post of DNA-encoded libraries (DELs) campaign is about a tool for DEL creation - eDESIGNER.

Last September, a group of researchers published a report called ‘Navigating the DNA encoded libraries chemical space’.

It describes the development and application of eDESIGNER, an algorithm that comprehensively generates all possible DNA- encoded library designs, and evaluates them to select the best ones to be synthesized.

The analysis is based on available BBs from various sources.

The tool is partially open-sourced at GitHub here: https://github.com/EliLillyCo/LillyMol.

Two previous posts are here and here.