News and Events

Fedratinib (INREBIC) is a drug used for the treatment of primary or secondary myelofibrosis. We have made a set of Building Blocks which contain this heterocycle–perfect start for your research.

Lasmiditan (REYVOW) is a drug used in the termination of migraine headaches approved by FDA in October 2019. It is a highly selective agonist of 5-HT1F receptors, carrying virtually no affinity for other receptors which appear to be largely responsible for the adverse effects (e.g. vasoconstriction) of its predecessors. Part of this molecule is a piperidine carboxylic acid – popular fragment in Drug Discovery. We have created a set of in-stock piperidine carboxylic acids Building Blocks to generate new ideas for your projects.

Zanubrutinib (BRUKINSA), approved by FDA in November 2019, used in the treatment of adult patients with mantle cell lymphoma (MCL), a form of blood cancer. It is an inhibitor of Bruton’s tyrosine kinase (BTK). Part of this molecule is a fused pyrazolopyrimidine cycle. We have created a set of Building Blocks, which contain this heterocycle, to generate new ideas for your projects.

A new release is coming up: +2 Billion compounds will be added soon! Navigate in 13 Billion compounds and place your orders through Chemspace. Drop us a line if you have any questions.

This time we would like to show you Azetidine derivatives, which are Molecules of This Week. We at ChemSpace always have new small molecules to power up your research. 

This time we would like to point at Fused Aromatic Heterocycle (Hetaryl) Acetonitriles, which are Molecules of This Week. We at Chemspace always have new small molecules to power up your research. In case of any questions just drop us a line: [email protected].

This time we would like to show you CHF₂-(Br,Cl)-Cyclohexanes, which are Molecules of This Week. We at ChemSpace always have new small molecules to power up your research. To browse the set please use this link. In case of any questions just drop us a line: [email protected].

This time we would like to point at Hetaryl Acetonitriles, which are Molecules of This Week. We at ChemSpace always have new small molecules to power up your research. To browse the set please use this link. In case of any questions just drop us a line: [email protected].

We are happy to announce a start of our collaboration with BioSolveIT! Now 11 Billion REAL Compounds are all searchable via Chemspace.

This time we would like to point at Fluorine-containing Aazetidines and Pyrrolidines, which are Molecules of This Week. We at ChemSpace always have new small molecules to power up your research. To browse the set please use this link to browse and purchase new organic chemistry. In case of any questions just drop us a line: [email protected].

This time we would like to point at Pyrazole containing thiols, which are Molecules of This Week. We at ChemSpace always have new small molecules to power up your research. To browse the set please use this link or visit chem-space.com to browse and purchase new organic chemistry. In case of any questions just drop us a line: [email protected].

This time we would like to point at Fluorine-Containing Spirocyclic Amines, which are Molecules of This Week. We at ChemSpace always have new small molecules to power up your research. To browse the set please use this link or visit chem-space.com to browse and purchase new organic chemistry. In case of any questions just drop us a line: [email protected].

Dear friends and colleagues! We would like to invite you to join Chemspace Webinar 'Application of Fragment Network to Chemspace database to find analogues', which will take place at 5PM (GMT+2) on September, 23.

Dear friends and colleagues! We would like to thank everyone who met us at ACS show this week! Hope to see you next year again!

This time we would like to point at Cyclic Amino Alcohols.

We at ChemSpace always have new small molecules to power up your research. To browse the set please use this link or visit chem-space.com to browse and purchase new organic chemistry. In case of any questions just drop us a line: [email protected].

Phenotypic screening (PS) is one of the two major approaches at early stage drug discovery projects, apart from the target-based screens. PS is focused on the overall effect a drug molecule causes in the cell rather than an effect found for a single target. To create Chemspace PS library, we have selected the compounds with activity annotations in ChEMBL from Chemspace Screening Compound set. Compounds have favorable physicochemical profiles. PAINS and toxic molecules have been removed. Each molecule is annotated with UniProt codes list of reported targets. Please use the link to download the set: https://bit.ly/2STV7cS or browse others Chemspace compound sets: https://lnkd.in/ddVRtBJ Also, our Summer Sale is on – order now, pay later, and save up to 15%!

In August 2018, FDA approved PIFELTRO (doravirine) as a HIV-1 infection drug. It contains 1,2,4-triazolone moiety in its backbone. This fact could not pass unnoticed. That is why we have prepared a set of 77 1,2,4-triazolones and their nearest derivatives to power up your research. 

Dear colleagues! We are looking forward to seeing you at the 258th ACS National Meeting & Exposition in August!

Molecules of the week are back! This time we would like to point at Saturated Aminonitriles. We at ChemSpace always have new small molecules to power up your research.

We are happy to annouce mega summer sale on all of our Compond Sets.

You can save up to 15%! Please use this link to browse through our Fragments, Screening Compounds, Building Blocks Compound Sets or contact us [email protected] to create a unique set only for you!

Visit our page of compound libraries to explore ALL of our Compound Sets!

To browse ALL our compound sets, please use this link: https://chem-space.com/compounds.

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized.

Compound Sets sale is coming soon! Please follow the updates. This summer is going to be special...

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized. https://bit.ly/2VKiomb