Warning!
Your browser does not support HTML5.
Display of the content may be incorrect. Please make sure that your browser supports HTML5 syntax.
Search for Small Molecules by SMILES, name, CAS, MFCD, ID, InChI Key
Search for Biologics by ID, Target name, CAS, Protein name, Gene ID, Clone ID, Source Organism
0
0.00 €
Currency
ListPlate
IUPAC Name: 
6-{3-[(4aR,7aS)-hexahydro-2H-[1,4]dioxino[2,3-c]pyrrol-6-yl]propoxy}-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine bis(methanesulfonic acid) hydrate
Supplier Lead time Price, € Pack
MedChemExpress
Ships from: United States
To:
10 days 240
Go to cartEnquire
Description: Names: Larotinib (mesylate hydrate); Product Description: Larotinib mesylate hydrate is a potent broad-spectrum and orally active tyrosine kinase inhibitor (TKI) with EGFR as the main target with an IC 50 of 0.6 nM .; Target: Btk;EGFR;IRAK; CAS: 2097129-93-4
MedChemExpress EU
Ships from: Sweden
To:
10 days 253
Go to cartEnquire
Description: Names: Larotinib (mesylate hydrate); Product Description: Larotinib mesylate hydrate is a potent broad-spectrum and orally active tyrosine kinase inhibitor (TKI) with EGFR as the main target with an IC50 of 0.6 nM; Target: Btk;EGFR;IRAK; CAS: 2097129-93-4
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSS07096521614 Add to cart
IUPAC Name: 
N-(3-chloro-4-fluorophenyl)-6-(2-{5,8-dioxa-10-azadispiro[2.0.4⁴.3³]undecan-10-yl}ethoxy)-7-methoxyquinazolin-4-amine
Supplier Lead time Price, € Pack
Angene International Limited
Ships from: China
To:
10 days 375
Go to cartEnquire
Description: Simotinib; CAS: 944258-89-3
Advanced ChemBlocks CN
Ships from: China
To:
12 days 195
Go to cartEnquire
Description: Simotinib; CAS: 944258-89-3
A2B Chem
Ships from: United States
To:
12 days 492
Go to cartEnquire
Description: Simotinib; CAS: 944258-89-3
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSB02515422213 Add to cart
IUPAC Name: 
N-(3-chloro-4-fluorophenyl)-6-(2-{5,8-dioxa-10-azadispiro[2.0.4⁴.3³]undecan-10-yl}ethoxy)-7-methoxyquinazolin-4-amine
Supplier Lead time Price, € Pack
MedChemExpress
Ships from: United States
To:
10 days 343
Go to cartEnquire
Description: Names: Simotinib; Product Description: Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC 50 of 19.9 nM. Antineoplastic activities .; Target: EGFR; CAS: 944258-89-3
MedChemExpress EU
Ships from: Sweden
To:
10 days 362
Go to cartEnquire
Description: Names: Simotinib; Product Description: Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities; Target: EGFR; CAS: 944258-89-3
Targetmol Chemicals Inc
Ships from: United States
To:
30 days
199
1 mg
Go to cartEnquire
Description: Simotinib (AL-6802) is a selective and orally bioactive EGFR tyrosine kinase inhibitor (IC50: 19.9 nM) with anti-tumour activity for the study of non-small cell lung cancer.; CAS: 944258-89-3
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSS02515422213 Add to cart
CAS: 1626387-95-8
IUPAC Name: 
4-tert-butyl 1-{4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl} (2R)-2-methylpiperazine-1,4-dicarboxylate
Supplier Lead time Price, € Pack
Advanced ChemBlocks CN
Ships from: China
To:
12 days 280
Go to cartEnquire
Description: (2R)-1,4-Piperazinedicarboxylic acid, 2-methyl-, 1-[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl] 4-(1,1-dimethylethyl) ester; CAS: 1626387-95-8
ChemScene CN
Ships from: China
To:
15 days 64
Go to cartEnquire
Description: 4-(tert-Butyl) 1-(4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl) (R)-2-methylpiperazine-1,4-dicarboxylate; CAS: 1626387-95-8
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSB06835378582 Add to cart
IUPAC Name: 
7-{[3-({4-[(3-chloro-4-fluorophenyl)amino]-6-methoxyquinazolin-7-yl}oxy)propyl]amino}-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
Supplier Lead time Price, € Pack
A2B Chem
Ships from: United States
To:
12 days 524
Go to cartEnquire
Description: HX103; CAS: 2566466-98-4
Angene US
Ships from: United States
To:
15 days 693
Go to cartEnquire
Description: HX103; CAS: 2566466-98-4
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSB06744480053 Add to cart
IUPAC Name: 
7-{[3-({4-[(3-chloro-4-fluorophenyl)amino]-6-methoxyquinazolin-7-yl}oxy)propyl]amino}-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
Supplier Lead time Price, € Pack
MedChemExpress
Ships from: United States
To:
10 days 368
Go to cartEnquire
Description: Names: HX103; Product Description: HX103 is an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe. HX103 inhibits EGFR 19 del , EGFR L858R , EGFR wild type and EGFR T790M with IC 50 s of 1.3, 1.5, 4.0 and 977 nM, respectively. HX103 can be used for quantifying active-EGFR to predict agent sensitivity in NSCLC patients with EGFR-activating mutations .; Target: EGFR; CAS: 2566466-98-4
MedChemExpress EU
Ships from: Sweden
To:
10 days 387
Go to cartEnquire
Description: Names: HX103; Product Description: HX103 is an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe. HX103 inhibits EGFR 19 del, EGFR L858R, EGFR wild type and EGFR T790M with IC50s of 1.3, 1.5, 4.0 and 977 nM, respectively. HX103 can be used for quantifying active-EGFR to predict agent sensitivity in NSCLC patients with EGFR-activating mutations; Target: EGFR; CAS: 2566466-98-4
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSS06744480053 Add to cart
IUPAC Name: 
3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
Supplier Lead time Price, € Pack
A2B Chem
Ships from: United States
To:
12 days
557
1 mg
Go to cartEnquire
Description: MS 154; CAS: 2550393-21-8
Angene US
Ships from: United States
To:
15 days
734
1 mg
Go to cartEnquire
Description: MS 154; CAS: 2550393-21-8
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSB06744481987 Add to cart
IUPAC Name: 
3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
Supplier Lead time Price, € Pack
MedChemExpress
Ships from: United States
To:
10 days 392
Go to cartEnquire
Description: Names: MS154; Product Description: MS154 is a first-in-class E3 ligase cereblon-recruiting EGFR degrader with K d s of 1.8 nM and 3.8 nM for EGFR WT and EGFR L858R mutants. MS154 potently induces the degradation of mutant but not wild-type EGFR in an E3 ligase-dependent manner in cancer cell lines. MS154 potently inhibits cell proliferation in lung cancer cells (Blue: E3 Ligase ligand (HY-103596); Black: linker (HY-W096167); Pink: EGFR ligand (HY-168305)) .; Target: EGFR;PROTACs; CAS: 2550393-21-8
MedChemExpress EU
Ships from: Sweden
To:
10 days 413
Go to cartEnquire
Description: Names: MS154; Product Description: MS154 is a first-in-class E3 ligase cereblon-recruiting EGFR degrader with Kds of 1.8 nM and 3.8 nM for EGFR WT and EGFR L858R mutants. MS154 potently induces the degradation of mutant but not wild-type EGFR in an E3 ligase-dependent manner in cancer cell lines. MS154 potently inhibits cell proliferation in lung cancer cells (Blue: E3 Ligase ligand (HY-103596); Black: linker (HY-W096167); Pink: EGFR ligand (HY-168305)); Target: EGFR;PROTACs; CAS: 2550393-21-8
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSS06744481987 Add to cart
IUPAC Name: 
3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
Supplier Lead time Price, € Pack
Angene US
Ships from: United States
To:
15 days
637
1 mg
Go to cartEnquire
Description: MS 154N; CAS: 2675490-97-6
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSB14855342051 Add to cart
IUPAC Name: 
3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
Supplier Lead time Price, € Pack
MedChemExpress
Ships from: United States
To:
10 days
333
1 mg
Go to cartEnquire
Description: Names: MS154N; Product Description: MS154N (compound 28) is the negative control of MS39 (HY-157581). MS154N is composed of PROTAC target protein ligand EGFR ligand-11 (HY-168305) (red part), E3 ligase ligand 4-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (HY-W441376) (blue part) and PROTAC Linker 8-Iodooctan-1-amine (HY-168306) (black part), among which the conjugate of E3 ubiquitin ligase ligand Linker is Me-Thalidomide-O-C8-NH2 (HY-168307) .; Target: EGFR;PROTACs; CAS: 2675490-97-6
MedChemExpress EU
Ships from: Sweden
To:
10 days
351
1 mg
Go to cartEnquire
Description: Names: MS154N; Product Description: MS154N (compound 28) is the negative control of MS39 (HY-157581). MS154N is composed of PROTAC target protein ligand EGFR ligand-11 (HY-168305) (red part), E3 ligase ligand 4-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (HY-W441376) (blue part) and PROTAC Linker 8-Iodooctan-1-amine (HY-168306) (black part), among which the conjugate of E3 ubiquitin ligase ligand Linker is Me-Thalidomide-O-C8-NH2 (HY-168307); Target: EGFR;PROTACs; CAS: 2675490-97-6
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSS14855342051 Add to cart
CAS: 2230821-27-7
IUPAC Name: 
(2S,4R)-1-[(2S)-2-[3-(2-{[5-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)pentyl]oxy}ethoxy)propanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
Supplier Lead time Price, € Pack
BLD Pharmatech Co., Limited
Ships from: United States
To:
1 day 16
Go to cartEnquire
Description: Name:(2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)pentyl)oxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CAS: 2230821-27-7
BLD PHARMATECH LTD CN
Ships from: China
To:
1 day 16
Go to cartEnquire
Description: Name:(2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)pentyl)oxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CAS: 2230821-27-7
BLD Pharmatech GmbH
Ships from: Germany
To:
1 day
99
25 mg
Go to cartEnquire
Description: Name:(2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)pentyl)oxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CAS: 2230821-27-7
Angene International Limited
Ships from: China
To:
5 days 16
Go to cartEnquire
Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
Astatech CN
Ships from: China
To:
10 days 186
Go to cartEnquire
Description: GEFITINIB-BASED PROTAC 3; CAS: 2230821-27-7
AA BLOCKS
Ships from: United States
To:
12 days 16
Go to cartEnquire
Description: Gefitinib-Based PROTAC 3; CAS: 2230821-27-7
A2B Chem
Ships from: United States
To:
12 days 29
Go to cartEnquire
Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
ChemScene CN
Ships from: China
To:
15 days 132
Go to cartEnquire
Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
Broadpharm
Ships from: United States
To:
20 days 94
Go to cartEnquire
Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSB00161189048 Add to cart
CAS: 2230821-27-7
IUPAC Name: 
(2S,4R)-1-[(2S)-2-[3-(2-{[5-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)pentyl]oxy}ethoxy)propanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
Supplier Lead time Price, € Pack
MedChemExpress
Ships from: United States
To:
10 days 129
Go to cartEnquire
Description: Names: Gefitinib-based PROTAC 3; Product Description: Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC 50 s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively .; Target: EGFR;PROTACs; CAS: 2230821-27-7
MedChemExpress EU
Ships from: Sweden
To:
10 days 136
Go to cartEnquire
Description: Names: Gefitinib-based PROTAC 3; Product Description: Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively; Target: EGFR;PROTACs; CAS: 2230821-27-7
Targetmol Chemicals Inc
Ships from: United States
To:
30 days 38
Go to cartEnquire
Description: Gefitinib-based PROTAC 3, which connects an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827 (exon 19 del) and H3255 (L858R mutation) cells, respectively[1].; CAS: 2230821-27-7
For a custom pack size or bulk
please drop us a line:Enquire
Zoom the structure CSSS00161189048 Add to cart
Showing 49-60 of 157 items.

Filter

Refine Query
New Search

Sort by

Filter by

Price
–
Lead time
–
Pack
Suppliers
Suppliers count
Properties
Molweight –
Heavy atom count –
Logp –
Rotatable bond count –
H-Bond donor count –
H-Bond acceptor count –
Cycle Count –
Fsp3 –
PSA, Å –
Countries
Remove all filters