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Home CSCS00016991211

1,4-diethyl (2Z)-but-2-enedioate

Structure Info

Chemspace ID
CSCS00016991211 (Synthesis)
CAS
141-05-9
MFCD
MFCD00009191
IUPAC Name
1,4-diethyl (2Z)-but-2-enedioate
Mol formula
C8H12O4
Mol weight
172 Da
Catalog Number(s)
141-05-9, 58455, A043, A200510, A490016045, AA001FN9, AA66833, ACM141059, ACM141059-2, ACM1410591, AG001FQ1, AI66833, AKOS015960830, AOS001FQ1, AP141059, AR001GF1, B6151, B697415, BB0294961, BB4LS-EN300-344747, BBV-108665411, BD124714, BS-15532, BUP17080, CD45000553, CM195302, CS-0017148, CSC016991211, D444535, D699054, D70233, EN300-344747, F1908-0131, F449208, FD38599, HY-Y1147, J95964, JH632682, LAN-B66846, LN00237957, LP018027, LP018030, M0010, M23567, OR1012871, PB3235043133, S4712, SAB-046949, T21480, Y1041231, Y4268704, Z3234965665, ZX-ARV15992, ZXC133017

Properties

LogP
1.43
Heavy atoms count
12
Rotatable bond count
6
Number of rings
0
Carbon bond saturation, Fsp3
0.5
Polar surface area (Å)
53
Hydrogen bond acceptors count
2
Hydrogen bond donors count
0

SDS

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C8H12O4
Zoom the structure
CSCS00016991211
 

Items Overall 27 items from 13 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
Molnova Chemicals10 daysUnited States
To:
98100 mg40.70
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Molnova Chemicals10 daysUnited States
To:
98200 mg67.10
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Molnova Chemicals10 daysUnited States
To:
98500 mg123.20
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Description: Diethylmaleate; CAS: 141-05-9
TCI America12 daysUnited States
To:
9025 ml19.20
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TCI America12 daysUnited States
To:
90500 ml43.20
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Description: CAS: 141-05-9
MedChemExpress30 daysUnited States
To:
99100 mg50.00
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MedChemExpress30 daysUnited States
To:
99500 mg90.00
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MedChemExpress30 daysUnited States
To:
991 g126.00
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MedChemExpress30 daysUnited States
To:
995 g189.00
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MedChemExpress30 daysUnited States
To:
9910 g265.00
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Description: Names: Diethyl maleate; Maleic acid diethyl ester; Product Description: Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO-. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases; Target: Biochemical Assay Reagents; CAS: 141-05-9
MedChemExpress EU30 daysSweden
To:
99100 mg50.00
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MedChemExpress EU30 daysSweden
To:
99500 mg90.00
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MedChemExpress EU30 daysSweden
To:
991 g126.00
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MedChemExpress EU30 daysSweden
To:
995 g189.00
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MedChemExpress EU30 daysSweden
To:
9910 g265.00
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Description: Names: Diethyl maleate; Maleic acid diethyl ester; Product Description: Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO-. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases; Target: Biochemical Assay Reagents; CAS: 141-05-9
eNovation CN40 daysChina
To:
95500 g80.50
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eNovation CN40 daysChina
To:
951 kg97.75
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eNovation CN40 daysChina
To:
9510 kg350.75
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Description: Diethyl (Z)-2-butenedioate; CAS: 141-05-9
Toronto Research Chemicals50 daysCanada
To:
905 g61.60
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Toronto Research Chemicals50 daysCanada
To:
9025 g74.80
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Description: Diethyl Maleate; Storage Condition: 4°C; CAS: 141-05-9
Alfa Chemistry Analytical Products7 daysUnited States
To:
901 gPOA
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Description: CAS: 141-05-9
LEAP CHEM Co., Ltd.15 daysChina
To:
951 gPOA
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Description: Diethyl fumarate; CAS: 623-91-6
AKos Consulting & Solutions GmbH30 daysGermany
To:
901 gPOA
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Apollo ScientificTBDUnited Kingdom
To:
951 gPOA
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Description: CAS: 141-05-9
Apollo Scientific USATBDUnited States
To:
951 gPOA
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Description: CAS: 141-05-9
BOC SciencesTBDUnited States
To:
951 gPOA
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Description: CAS: 141-05-9
Crysdot LLCTBDUnited States
To:
951 gPOA
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Description: CAS: 141-05-9
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