1-aminocyclopropane-1-carboxylic acid
Structure Info
- Chemspace ID
- CSSS00000746478 (In-Stock Screening Compounds)
- CAS
- 22059-21-8
- MFCD
- MFCD00009944, MFCD00083285, MFCD00009944
- IUPAC Name
- 1-aminocyclopropane-1-carboxylic acid
- Mol formula
- C4H7NO2
- Mol weight
- 101 Da
- Catalog Number(s)
- 7075, 07075, 16132, 22059-21-8, 26804, 83039, 152473, 341640, 12488936, 80010568, A1-00274, A1178, A176440, A490015581, A603550, AA0032LK, AB11249, AB43236, AC010568, ACDS-032973, AG0032OC, AJ43236, AKOS005145951, AOS0032OC, AP22059218-A, AP22059218-B, AR0033DC, AX145204, ArZ-UP060970, BAT-008128, BB4LS-PS-9319, BBV-38409013, BIA1373, BUP17509, BW10936, CB03215, CD21010279, CM105059, CP20101, CS-B0091, CS-W014159, CSC000746478, CSC121590733, D210305, D382441, D497162, D686963, EN300-57568, F043411, F8889-0699, FA10789, G-5950, H949121, HTS042643, HY-30004, IN1537, J-504203, J90725, JH657530, K924, LAN-B01400, LP059027, LQT-B01407, M19578, MTL22059218, NA-0273, OR0355T, OSSM_263234, P50623, PB126377, PS-9319, R150518, RS20006623, SC-11059, SC-11062, SY002598, T4752, TX0033U0, V24455, Y043-8333, ZX-AE000671, sdv-4307
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- -2.72
- Heavy atoms count
- 7
- Rotatable bond count
- 1
- Number of rings
- 1
- Carbon bond saturation, Fsp3
- 0.75
- Polar surface area (Å)
- 63
- Hydrogen bond acceptors count
- 3
- Hydrogen bond donors count
- 2
- Zoom the structure
- CSSS00000746478
Items Overall 33 items from 5 suppliers
| Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
|---|---|---|---|---|---|---|
| Key Organics Limited (BIONET) | 10 days | United Kingdom To: | 95 | 1 mg | 55.00 | |
| Key Organics Limited (BIONET) | 10 days | United Kingdom To: | 95 | 5 mg | 68.20 | |
| Key Organics Limited (BIONET) | 10 days | United Kingdom To: | 95 | 10 mg | 93.50 | |
| MedChemExpress | 10 days | United States To: | 99 | 500 mg | 55.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 1 g | 83.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 5 g | 150.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 10 g | 195.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 25 g | 312.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 50 g | 375.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 100 g | 450.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 1 ml | 60.00 | |
Description: Names: 1-Aminocyclopropane-1-carboxylic acid; Product Description: 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity.; Target: Endogenous Metabolite; CAS: 22059-21-8 | ||||||
| MedChemExpress EU | 10 days | Sweden To: | 99 | 500 mg | 55.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 1 g | 83.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 5 g | 150.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 10 g | 195.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 25 g | 312.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 50 g | 375.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 100 g | 450.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 1 ml | 60.00 | |
Description: Names: 1-Aminocyclopropane-1-carboxylic acid; Product Description: 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity.; Target: Endogenous Metabolite; CAS: 22059-21-8 | ||||||
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 1 mg | 88.00 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 2 mg | 93.50 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 5 mg | 107.80 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 10 mg | 118.80 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 15 mg | 132.00 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 20 mg | 145.20 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 30 mg | 165.00 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 50 mg | 231.00 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 100 mg | 319.00 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 3 umol | 93.50 | |
| Princeton Biomolecular Research | 10 days | United States To: | 90 | 5 umol | 99.00 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 200 mg | 30.00 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 500 mg | 44.00 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 1 g | 66.00 | |
Description: 1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecule agonist at the glycine modulatory site of the NMDA receptor (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate.2 This compound has been reported to protect against neuron cell death in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.; CAS: 22059-21-8 | ||||||
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