(1R,2S,6S,9S,10S,11R,14S,15S,18S,20S,23R,24S)-10,20-dihydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁴.0¹⁸,²³]pentacosan-17-one
Structure Info
- Chemspace ID
- CSSS00102419924 (In-Stock Screening Compounds)
- CAS
- 61825-98-7
- MFCD
- MFCD00171661
- IUPAC Name
- (1R,2S,6S,9S,10S,11R,14S,15S,18S,20S,23R,24S)-10,20-dihydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁴.0¹⁸,²³]pentacosan-17-one
- Mol formula
- C27H43NO3
- Mol weight
- 430 Da
- Catalog Number(s)
- 42887, 42887-0.1G, 42887-0.5G, 474264, AA00EBEH, ACM61825987, AG00EBH9, AG67861, AO67861, AOS00EBH9, AP61825987, AR00EC69, ArZ-UP487504, B2703-465209, BBP03804, BD134509, BUP03334, CD32000807, CFN99711, CSC102419924, D511765, FS73809, HY-N0696, I492500, IBS-E0731093, LN01341695, MS-27627, N2485, NP-022229, NP0527, S9233, T6S0109, TX00ECMX, U106930, Y6021033, ZX-CY009280
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 3.22
- Heavy atoms count
- 31
- Rotatable bond count
- 0
- Number of rings
- 6
- Carbon bond saturation, Fsp3
- 0.962
- Polar surface area (Å)
- 61
- Hydrogen bond acceptors count
- 4
- Hydrogen bond donors count
- 2
- Zoom the structure
- CSSS00102419924
Items Overall 31 items from 6 suppliers
| Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
|---|---|---|---|---|---|---|
| MedChemExpress | 10 days | United States To: | 99 | 5 mg | 57.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 10 mg | 86.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 25 mg | 156.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 50 mg | 234.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 100 mg | 351.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 250 mg | 632.00 | |
| MedChemExpress | 10 days | United States To: | 99 | 1 ml | 62.00 | |
Description: Names: Sipeimine; Imperialine; Product Description: Sipeimine (Imperialine) is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65. Sipeimine inhibits PI3K/AKT phosphorylation, blocks NF-κB nuclear translocation and NLRP3 inflammasome activation. Sipeimine exerts anti-inflammatory activities, inhibits pyroptosis and ferroptosis, and protects the extracellular matrix. Sipeimine can reduce cartilage degradation and synovial inflammation in osteoarthritis and improve PM2.5-induced lung injury. Sipeimine is mainly used in the study of anti-inflammatory and degenerative diseases; Target: Akt;Ferroptosis;NF-κB;NOD-like Receptor (NLR);PI3K;Pyroptosis; CAS: 61825-98-7 | ||||||
| MedChemExpress EU | 10 days | Sweden To: | 99 | 5 mg | 57.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 10 mg | 86.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 25 mg | 156.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 50 mg | 234.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 100 mg | 351.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 250 mg | 632.00 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 1 ml | 62.00 | |
Description: Names: Sipeimine; Imperialine; Product Description: Sipeimine (Imperialine) is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65. Sipeimine inhibits PI3K/AKT phosphorylation, blocks NF-κB nuclear translocation and NLRP3 inflammasome activation. Sipeimine exerts anti-inflammatory activities, inhibits pyroptosis and ferroptosis, and protects the extracellular matrix. Sipeimine can reduce cartilage degradation and synovial inflammation in osteoarthritis and improve PM2.5-induced lung injury. Sipeimine is mainly used in the study of anti-inflammatory and degenerative diseases; Target: Akt;Ferroptosis;NF-κB;NOD-like Receptor (NLR);PI3K;Pyroptosis; CAS: 61825-98-7 | ||||||
| Apexbio Technology LLC | 10 days | United States To: | 98 | 20 mg | 396.00 | |
Description: Sipeimine; CAS: 61825-98-7 | ||||||
| ChemFaces | 12 days | China To: | 90 | 1 mg | 15.00 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 1 mg | 339.90 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 2 mg | 425.70 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 5 mg | 682.00 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 10 mg | 1,111.00 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 15 mg | 1,446.50 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 20 mg | 1,784.20 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 25 mg | 2,093.30 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 30 mg | 2,403.50 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 50 mg | 3,544.20 | |
| AnalytiCon Discovery GmbH | 15 days | Germany To: | 90 | 100 mg | 7,084.00 | |
Description: CAS: 61825-98-7 | ||||||
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 2 mg | 30.00 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 5 mg | 45.00 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 10 mg | 68.00 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 25 mg | 127.00 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 99 | 50 mg | 192.00 | |
Description: 1. Sipeimine (Kashmirine) has antiasthmatic effect, on tracheal M receptor antagonist. 2. Sipeimine can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve to the right.; CAS: 61825-98-7 | ||||||
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