Explore the mysteries of Janus kinases (JAKs) with Chemspace's Biologics set. It is designed to advance research into JAK kinase-related pathways, clarifying their roles in both physiological and pathological processes.
JAKs are a family of intracellular, non-receptor tyrosine kinases consisting of four enzymes: JAK1, JAK2, JAK3, and TYK2. They are key mediators in the JAK-STAT signaling pathway, a fundamental mechanism that transmits extracellular signals into cellular responses. This pathway is involved in numerous biological processes, including immune system regulation, hematopoiesis, cell growth and differentiation, inflammatory responses, and oncogenesis. Dysregulation of JAK-STAT signaling is implicated in various pathological conditions, such as autoimmune disorders, hematological malignancies, solid tumors, inflammatory diseases, metabolic syndrome, etc.
Chemspace's Biologics set equips researchers with the tools to investigate JAKs in diverse contexts. By leveraging it, you can accelerate your studies into JAK-mediated signaling, deepening the understanding of mechanisms of both normal cellular processes and disease.
Chemspace offers a comprehensive selection of 486K Biologics, including peptides, proteins, and antibodies, as well as biological services. Interested or have any questions? Contact us at sales@chem-space.com.