Discover Orexin receptors, a crucial therapeutic target for treating sleep disorders and other neurological conditions. We have prepared a selected set of Biologics for your future studying Orexin receptor-related diseases.
Orexin receptors (also known as hypocretin receptors), specifically Orexin 1 (OX1R) and Orexin 2 (OX2R), are G-protein-coupled receptors that play a significant role in regulating arousal, wakefulness, and appetite. These receptors are primarily expressed in the hypothalamus and have been implicated in various biological processes, including sleep-wake regulation.
Orexin receptors were discovered only at the end of the 20th century and remain relevant targets today. Recently, Janssen announced that their drug candidate Seltorexant, targeting OX2R, shows significant improvements in patients with major depressive disorder and insomnia.
Chemspace offers a comprehensive selection of 486K Biologics, including peptides, proteins, and antibodies, as well as biological services. Interested or have any questions? Contact us at info@chem-space.com.