Most virtual screening workflows face the same constraint: the further you scale, the harder it becomes to navigate with confidence. Coverage alone is not enough - the tools you use to traverse the space determine whether you find actionable hits.
We partner with computational chemistry platforms to ensure Freedom Space 5.0 is accessible within the tools discovery teams rely on. The latest integration brings Freedom Space 5.0 directly into Alipheron's tools (https://alipheron.com/).
Pharos-3D applies a 3D-similarity search method that combines 3D shape and pharmacophore models, enabling retrieval based on how molecules actually behave in 3D space - not just structural fingerprints.
Hyperspace Search provides 2D virtual screening for precise substructure and structure similarity search, optimized for large-scale enumerated spaces.
Freedom Space 5.0 is an ultra-large chemical space containing 296 billion molecules, built using machine learning models to evaluate building blocks for synthetic feasibility before enumeration - delivering an experimentally confirmed synthesis success rate of over 80%.
