We are excited to announce that Freedom Space 4.0 is now accessible for screening using Alipheron’s latest powerful tool, Pharos-3D. This advanced technology enables researchers to find those molecules that match the query molecule well with respect to shape and functional overlap in similar interaction points with their target.

 

Why use Pharos-3D?

  • It is a 3D-based search! Pharos-3D identifies molecules whose three-dimensional shape and pharmacophore features match a bioactive query conformation, improving the chance of finding functionally similar hits
  • Pharos-3D searches all low-energy conformers, going beyond 2D similarity to find molecules that optimize a match to the target’s 3D shape closely.
  • User-friendly: Either fully integrated into DataWarrior, allowing you to work in a familiar environment with a simple workflow, or accessible via API to embed it into existing automated pipelines
  • Accessible & Flexible: License- or credit-based usage makes this advanced shape/pharmacophore screening technology available to everyone

 

More about Pharos-3D here: https://www.alipheron.com/products/pharos/

Explore Freedom Space 4.0: https://chem-space.com/freedom-space