This May, a group of researchers published a miniperspective on the importance of isosteres for epigenetic drug discovery. They summed up the frequency of various post-translationally modified lysine bioisosteres found in different compound collections, discovering general trends.

We at Chemspace prepared 3 great sets of compounds based on oxazole, triazole and pyridone moieties!
You can check them out using these links:

Oxazole set - 1327 compounds   
Triazole set - 1150 compounds
Pyridone set - 755 compounds

In case of any questions just drop us a line: info@chem-space.com.