Chemspace, LLC, Enamine, Ltd., and Orogen Therapeutics are excited to announce a strategic collaboration to enable next-generation REAL-driven DNA-encoded small molecule libraries (DELs). This partnership brings together the complementary strengths of the three companies to accelerate the search for innovative medicines.

By harnessing Orogen’s DEL- and AI-enabled platform, including FocusDEL™ technology, Chemspace’s chemi-informatics and synthetic capabilities, and Enamine’s REAL Space design principles, the collaboration opens access to a vast and diverse chemical universe for drug discovery. This integrated approach streamlines the process from initial screening to the development of optimized compounds, enabling faster and more efficient identification of novel drug candidates across a range of therapeutic areas, including immuno-inflammatory disorders, oncology, and GPCR targets.

Read the full press release here: https://www.businesswire.com/news/home/20250716264196/en/Orogen-Therapeutics-and-ChemspaceEnamine-Announce-a-Strategic-Collaboration-to-Enable-Unique-REAL-Driven-DNA-Encoded-Small-Molecule-Libraries