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CAS: 22059-21-8
IUPAC Name: 
1-aminocyclopropane-1-carboxylic acid
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Description: Names: 1-Aminocyclopropane-1-carboxylic acid; Product Description: 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity.; Target: Endogenous Metabolite; CAS: 22059-21-8
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Description: Names: 1-Aminocyclopropane-1-carboxylic acid; Product Description: 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity.; Target: Endogenous Metabolite; CAS: 22059-21-8
Princeton Biomolecular Research
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Description: 1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecule agonist at the glycine modulatory site of the NMDA receptor (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate.2 This compound has been reported to protect against neuron cell death in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.; CAS: 22059-21-8
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CAS: 68781-13-5
IUPAC Name: 
1-aminocyclopropane-1-carboxylic acid hydrochloride
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Enamine Ltd.
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CAS: 22264-50-2
IUPAC Name: 
1-aminocyclobutane-1-carboxylic acid
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Description: Names: 1-Aminocyclobutanecarboxylic acid; Product Description: 1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1; Target: iGluR; CAS: 22264-50-2
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Description: Names: 1-Aminocyclobutanecarboxylic acid; Product Description: 1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1; Target: iGluR; CAS: 22264-50-2
Key Organics Limited (BIONET)
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Princeton Biomolecular Research
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Apexbio Technology LLC
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Description: Name: ACBC; NMDA receptor partial agonist; Format: white solid; CAS: 22264-50-2
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Description: 1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].; CAS: 22264-50-2
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CAS: 52-52-8
IUPAC Name: 
1-aminocyclopentane-1-carboxylic acid
Dangerous substance
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Description: Names: Cycloleucine; Product Description: Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of ATP: L-methionine-S-adenosyl transferase in vitro. Cycloleucine has anxiolytic and cytostatic effects; Target: iGluR; CAS: 52-52-8
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Description: Names: Cycloleucine; Product Description: Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of ATP: L-methionine-S-adenosyl transferase in vitro. Cycloleucine has anxiolytic and cytostatic effects; Target: iGluR; CAS: 52-52-8
Princeton Biomolecular Research
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Enamine Ltd.
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Description: Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of S-adenosyl-methionine mediated methylation with anxiolytic and cytostatic effects.; CAS: 52-52-8
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CAS: 1240529-10-5
IUPAC Name: 
1-amino-4,4-difluorocyclohexane-1-carboxylic acid
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Description: 1-Amino-4,4-difluorocyclohexane-1-carboxylic acid is a fluoride analog involved in the synthesis of insecticides, herbicides, and fungicides.; CAS: 1240529-10-5
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CAS: 6949-77-5
IUPAC Name: 
1-aminocycloheptane-1-carboxylic acid
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Enamine Ltd.
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Princeton Biomolecular Research
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CAS: 2756-85-6
IUPAC Name: 
1-aminocyclohexane-1-carboxylic acid
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Key Organics Limited (BIONET)
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CAS: 98071-16-0
IUPAC Name: 
1-aminocyclobutane-1-carboxylic acid hydrochloride
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CAS: 1430854-20-8
IUPAC Name: 
1-amino-4,4-difluorocyclohexane-1-carboxylic acid hydrochloride
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Enamine Ltd.
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UORSY
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CAS: 39124-16-8, 7357-67-7
IUPAC Name: 
4-aminothiane-4-carboxylic acid
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Key Organics Limited (BIONET)
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CAS: 39124-20-4, 1156155-58-6
IUPAC Name: 
4-aminooxane-4-carboxylic acid
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Enamine Ltd.
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FCH Group
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CAS: 1803601-45-7
IUPAC Name: 
1-amino-4,4-dimethylcyclohexane-1-carboxylic acid hydrochloride
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