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CAS: 1626387-95-8
IUPAC Name: 
4-tert-butyl 1-{4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl} (2R)-2-methylpiperazine-1,4-dicarboxylate
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ChemScene LLC
Ships from: United States
To:
15 days 64
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Description: 4-(tert-Butyl) 1-(4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl) (R)-2-methylpiperazine-1,4-dicarboxylate; CAS: 1626387-95-8
Advanced ChemBlock Inc
Ships from: United States
To:
30 days 280
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Description: (2R)-1,4-Piperazinedicarboxylic acid, 2-methyl-, 1-[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl] 4-(1,1-dimethylethyl) ester; CAS: 1626387-95-8
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IUPAC Name: 
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]-N-[3-(morpholin-4-yl)propyl]quinazolin-4-amine
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AA BLOCKS
Ships from: United States
To:
35 days 1,009
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Description: N-(3-chloro-4-fluorophenyl)-7; CAS: 1502829-45-9
A2B Chem
Ships from: United States
To:
35 days 1,091
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Description: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine; CAS: 1502829-45-9
Toronto Research Chemicals
Ships from: Canada
To:
50 days 776
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Description: N-(3-Morpholinopropyl) Gefitinib; Storage Condition: -20°C; CAS: 1502829-45-9
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IUPAC Name: 
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]-N-{3-[(2,2,3,3,5,5,6,6-²H₈)morpholin-4-yl]propyl}quinazolin-4-amine
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Toronto Research Chemicals
Ships from: Canada
To:
50 days
1,425
10 mg
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Description: N-(3-Morpholinopropyl) Gefitinib-D8
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IUPAC Name: 
7-{[3-({4-[(3-chloro-4-fluorophenyl)amino]-6-methoxyquinazolin-7-yl}oxy)propyl]amino}-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
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Angene International Limited
Ships from: China
To:
15 days 726
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Description: HX103; CAS: 2566466-98-4
Targetmol Chemicals Inc
Ships from: United States
To:
TBD
POA
1 mg
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Description: HX103, an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe, exhibits selective inhibition towards various EGFR mutations, including EGFR 19 del, EGFR L858R, EGFR wild type, and EGFR T790M, with respective IC50 values of 1.3, 1.5, 4.0, and 977 nM. It is utilized for quantifying active-EGFR to foresee agent sensitivity in NSCLC (non-small cell lung cancer) patients harboring EGFR-activating mutations [1].; CAS: 2566466-98-4
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IUPAC Name: 
N-{3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}-7-methoxy-6-[4-(2-nitro-1H-imidazol-1-yl)butoxy]quinazolin-4-amine
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MedChemExpress
Ships from: United States
To:
TBD
POA
1 mg
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Description: Names: EGFR/HER2-IN-10; Product Description: EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC 50 s of 2.3 nM and 234 nM for EGFR and HER2, respectively. EGFR/HER2-IN-10 shows an effective antiproliferative action against prostate carcinoma .; Target: EGFR; CAS: 2931499-82-8
MedChemExpress EU
Ships from: Sweden
To:
TBD
POA
1 mg
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Description: Names: EGFR/HER2-IN-10; Product Description: EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC50s of 2.3 nM and 234 nM for EGFR and HER2, respectively. EGFR/HER2-IN-10 shows an effective antiproliferative action against prostate carcinoma; Target: EGFR; CAS: 2931499-82-8
Targetmol Chemicals Inc
Ships from: United States
To:
TBD
POA
1 mg
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Description: EGFR/HER2-IN-10 (compound 9F) serves as a potent, selective dual inhibitor for EGFR and HER2, exhibiting IC50 values of 2.3 nM for EGFR and 234 nM for HER2. Additionally, it demonstrates effective antiproliferative activity against prostate carcinoma [1].; CAS: 2931499-82-8
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IUPAC Name: 
N-(3-chloro-2-fluorophenyl)-6-[4-({[2,6-dimethoxy-4-({2-methyl-[1,1'-biphenyl]-3-yl}methoxy)phenyl]methyl}amino)butoxy]-7-methoxyquinazolin-4-amine
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MedChemExpress
Ships from: United States
To:
TBD
POA
1 mg
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Description: Names: EP26; Product Description: EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC 50 values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma .; Target: EGFR;PD-1/PD-L1
MedChemExpress EU
Ships from: Sweden
To:
TBD
POA
1 mg
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Description: Names: EP26; Product Description: EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC50 values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma; Target: EGFR;PD-1/PD-L1
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IUPAC Name: 
N-[2-(2-{2-[2-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)ethoxy]ethoxy}ethoxy)ethyl]-2-(2,6-dibromo-4-{[(3E)-5-iodo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}phenoxy)acetamide
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Enamine Ltd
Ships from: Ukraine
To:
20 days
3,953
1 g
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IUPAC Name: 
N-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]-6-[(2-{4-[(1Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)(methyl)amino]hexanamide
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MedChemExpress
Ships from: United States
To:
TBD
POA
1 mg
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Description: Names: EGFR-IN-42; Product Description: EGFR-IN-42 (Compound 17b) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-42 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-42 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-42 has superior anti-cancer activity .; Target: EGFR; CAS: 3031307-73-7
MedChemExpress EU
Ships from: Sweden
To:
TBD
POA
1 mg
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Description: Names: EGFR-IN-42; Product Description: EGFR-IN-42 (Compound 17b) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-42 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-42 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-42 has superior anti-cancer activity; Target: EGFR; CAS: 3031307-73-7
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IUPAC Name: 
N-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]-7-[(2-{4-[(1Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)(methyl)amino]heptanamide
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MedChemExpress
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To:
TBD
POA
1 mg
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Description: Names: EGFR-IN-43; Product Description: EGFR-IN-43 (Compound 17c) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-43 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-43 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-43 has superior anti-cancer activity .; Target: EGFR; CAS: 3031307-74-8
MedChemExpress EU
Ships from: Sweden
To:
TBD
POA
1 mg
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Description: Names: EGFR-IN-43; Product Description: EGFR-IN-43 (Compound 17c) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-43 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-43 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-43 has superior anti-cancer activity; Target: EGFR; CAS: 3031307-74-8
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IUPAC Name: 
3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
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Angene International Limited
Ships from: China
To:
15 days
769
1 mg
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Description: MS 154; CAS: 2550393-21-8
Targetmol Chemicals Inc
Ships from: United States
To:
TBD
POA
1 mg
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Description: MS 154 is a potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant epidermal growth factor receptor (EGFR), comprising a cereblon-binding moiety joined by a linker to gefitinib(Iressa). MS 154 decreases EGFR protein levels, inhibits downstream signaling in and inhibits proliferation of mutant EGFR-bearing lung cancer cells (DC50values are 11 and 25 nM in HCC-827 and H3255 cells, respectively; Dmax> 95% at 50 nM), but not in WT-EGFR-bearing ovarian and lung cancer cells lines. Bioavailable in mice following ip administration.; CAS: 2550393-21-8
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IUPAC Name: 
3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
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Angene International Limited
Ships from: China
To:
15 days
668
1 mg
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Description: MS 154N; CAS: 2675490-97-6
Targetmol Chemicals Inc
Ships from: United States
To:
TBD
POA
1 mg
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Description: MS 154N is a negative control for MS 154. The compound exhibits high binding-affinity for WT and L858R-mutant EGFR (Kdvalues are 3 and 4.3 nM, respectively), but does not significantly induce degradation of EGFR mutants.; CAS: 2675490-97-6
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CAS: 2230821-27-7
IUPAC Name: 
(2S,4R)-1-[(2S)-2-[3-(2-{[5-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)pentyl]oxy}ethoxy)propanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
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Angene US
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To:
5 days 16
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Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
APPCHEM Limited
Ships from: China
To:
14 days 18
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Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
ChemScene LLC
Ships from: United States
To:
15 days 132
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Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
ChemShuttle
Ships from: United States
To:
28 days
385
100 mg
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Apollo Scientific
Ships from: United Kingdom
To:
TBD
POA
1 g
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Description: CAS: 2230821-27-7
Apollo Scientific USA
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 2230821-27-7
Chiralstar, Inc.
Ships from: United States
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TBD
POA
1 g
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Description: CAS: 2230821-27-7
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Showing 133-144 of 157 items.

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