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CAS: 1626387-95-8IUPAC Name:4-tert-butyl 1-{4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl} (2R)-2-methylpiperazine-1,4-dicarboxylate
Supplier Lead time Price, $ Pack ChemScene LLCShips from: United StatesTo:15 days 64 Description: 4-(tert-Butyl) 1-(4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl) (R)-2-methylpiperazine-1,4-dicarboxylate; CAS: 1626387-95-8Advanced ChemBlock IncShips from: United StatesTo:30 days 280 Description: (2R)-1,4-Piperazinedicarboxylic acid, 2-methyl-, 1-[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl] 4-(1,1-dimethylethyl) ester; CAS: 1626387-95-8For a custom pack size or bulk
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IUPAC Name:N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]-N-[3-(morpholin-4-yl)propyl]quinazolin-4-amine
Supplier Lead time Price, $ Pack AA BLOCKSShips from: United StatesTo:35 days 1,009 Description: N-(3-chloro-4-fluorophenyl)-7; CAS: 1502829-45-9A2B ChemShips from: United StatesTo:35 days 1,091 Description: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine; CAS: 1502829-45-9Toronto Research ChemicalsShips from: CanadaTo:50 days 776 Description: N-(3-Morpholinopropyl) Gefitinib; Storage Condition: -20°C; CAS: 1502829-45-9For a custom pack size or bulk
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IUPAC Name:N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]-N-{3-[(2,2,3,3,5,5,6,6-²H₈)morpholin-4-yl]propyl}quinazolin-4-amine
Supplier Lead time Price, $ Pack Toronto Research ChemicalsShips from: CanadaTo:50 days 1,42510 mgDescription: N-(3-Morpholinopropyl) Gefitinib-D8For a custom pack size or bulk
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IUPAC Name:7-{[3-({4-[(3-chloro-4-fluorophenyl)amino]-6-methoxyquinazolin-7-yl}oxy)propyl]amino}-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
Supplier Lead time Price, $ Pack Angene International LimitedShips from: ChinaTo:15 days 726 Description: HX103; CAS: 2566466-98-4Targetmol Chemicals IncShips from: United StatesTo:TBD POA1 mgDescription: HX103, an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe, exhibits selective inhibition towards various EGFR mutations, including EGFR 19 del, EGFR L858R, EGFR wild type, and EGFR T790M, with respective IC50 values of 1.3, 1.5, 4.0, and 977 nM. It is utilized for quantifying active-EGFR to foresee agent sensitivity in NSCLC (non-small cell lung cancer) patients harboring EGFR-activating mutations [1].; CAS: 2566466-98-4For a custom pack size or bulk
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IUPAC Name:N-{3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}-7-methoxy-6-[4-(2-nitro-1H-imidazol-1-yl)butoxy]quinazolin-4-amine
Supplier Lead time Price, $ Pack MedChemExpressShips from: United StatesTo:TBD POA1 mgDescription: Names: EGFR/HER2-IN-10; Product Description: EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC 50 s of 2.3 nM and 234 nM for EGFR and HER2, respectively. EGFR/HER2-IN-10 shows an effective antiproliferative action against prostate carcinoma .; Target: EGFR; CAS: 2931499-82-8MedChemExpress EUShips from: SwedenTo:TBD POA1 mgDescription: Names: EGFR/HER2-IN-10; Product Description: EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC50s of 2.3 nM and 234 nM for EGFR and HER2, respectively. EGFR/HER2-IN-10 shows an effective antiproliferative action against prostate carcinoma; Target: EGFR; CAS: 2931499-82-8Targetmol Chemicals IncShips from: United StatesTo:TBD POA1 mgDescription: EGFR/HER2-IN-10 (compound 9F) serves as a potent, selective dual inhibitor for EGFR and HER2, exhibiting IC50 values of 2.3 nM for EGFR and 234 nM for HER2. Additionally, it demonstrates effective antiproliferative activity against prostate carcinoma [1].; CAS: 2931499-82-8For a custom pack size or bulk
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IUPAC Name:N-(3-chloro-2-fluorophenyl)-6-[4-({[2,6-dimethoxy-4-({2-methyl-[1,1'-biphenyl]-3-yl}methoxy)phenyl]methyl}amino)butoxy]-7-methoxyquinazolin-4-amine
Supplier Lead time Price, $ Pack MedChemExpressShips from: United StatesTo:TBD POA1 mgDescription: Names: EP26; Product Description: EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC 50 values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma .; Target: EGFR;PD-1/PD-L1MedChemExpress EUShips from: SwedenTo:TBD POA1 mgDescription: Names: EP26; Product Description: EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC50 values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma; Target: EGFR;PD-1/PD-L1For a custom pack size or bulk
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IUPAC Name:N-[2-(2-{2-[2-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)ethoxy]ethoxy}ethoxy)ethyl]-2-(2,6-dibromo-4-{[(3E)-5-iodo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}phenoxy)acetamideFor a custom pack size or bulk
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IUPAC Name:N-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]-6-[(2-{4-[(1Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)(methyl)amino]hexanamide
Supplier Lead time Price, $ Pack MedChemExpressShips from: United StatesTo:TBD POA1 mgDescription: Names: EGFR-IN-42; Product Description: EGFR-IN-42 (Compound 17b) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-42 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-42 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-42 has superior anti-cancer activity .; Target: EGFR; CAS: 3031307-73-7MedChemExpress EUShips from: SwedenTo:TBD POA1 mgDescription: Names: EGFR-IN-42; Product Description: EGFR-IN-42 (Compound 17b) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-42 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-42 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-42 has superior anti-cancer activity; Target: EGFR; CAS: 3031307-73-7For a custom pack size or bulk
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IUPAC Name:N-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]-7-[(2-{4-[(1Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)(methyl)amino]heptanamide
Supplier Lead time Price, $ Pack MedChemExpressShips from: United StatesTo:TBD POA1 mgDescription: Names: EGFR-IN-43; Product Description: EGFR-IN-43 (Compound 17c) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-43 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-43 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-43 has superior anti-cancer activity .; Target: EGFR; CAS: 3031307-74-8MedChemExpress EUShips from: SwedenTo:TBD POA1 mgDescription: Names: EGFR-IN-43; Product Description: EGFR-IN-43 (Compound 17c) is a potent inhibitor of EGFR with single-digit nanomolar activity. EGFR-IN-43 connects tamoxifen or endoxifen with the EGFR-inhibitor gefitinib via a covalent linkage. EGFR-IN-43 retains both ER antagonist activity and EGFR inhibition. EGFR-IN-43 has superior anti-cancer activity; Target: EGFR; CAS: 3031307-74-8For a custom pack size or bulk
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IUPAC Name:3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
Supplier Lead time Price, $ Pack Angene International LimitedShips from: ChinaTo:15 days 7691 mgDescription: MS 154; CAS: 2550393-21-8Targetmol Chemicals IncShips from: United StatesTo:TBD POA1 mgDescription: MS 154 is a potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant epidermal growth factor receptor (EGFR), comprising a cereblon-binding moiety joined by a linker to gefitinib(Iressa). MS 154 decreases EGFR protein levels, inhibits downstream signaling in and inhibits proliferation of mutant EGFR-bearing lung cancer cells (DC50values are 11 and 25 nM in HCC-827 and H3255 cells, respectively; Dmax> 95% at 50 nM), but not in WT-EGFR-bearing ovarian and lung cancer cells lines. Bioavailable in mice following ip administration.; CAS: 2550393-21-8For a custom pack size or bulk
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IUPAC Name:3-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-N-(8-{[2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}octyl)propanamide
Supplier Lead time Price, $ Pack Angene International LimitedShips from: ChinaTo:15 days 6681 mgDescription: MS 154N; CAS: 2675490-97-6Targetmol Chemicals IncShips from: United StatesTo:TBD POA1 mgDescription: MS 154N is a negative control for MS 154. The compound exhibits high binding-affinity for WT and L858R-mutant EGFR (Kdvalues are 3 and 4.3 nM, respectively), but does not significantly induce degradation of EGFR mutants.; CAS: 2675490-97-6For a custom pack size or bulk
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CAS: 2230821-27-7IUPAC Name:(2S,4R)-1-[(2S)-2-[3-(2-{[5-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)pentyl]oxy}ethoxy)propanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
Supplier Lead time Price, $ Pack Angene USShips from: United StatesTo:5 days 16 Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7APPCHEM LimitedShips from: ChinaTo:14 days 18 Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7ChemScene LLCShips from: United StatesTo:15 days 132 Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7ChemShuttleShips from: United StatesTo:28 days 385100 mgApollo ScientificShips from: United KingdomTo:TBD POA1 gDescription: CAS: 2230821-27-7Apollo Scientific USAShips from: United StatesTo:TBD POA1 gDescription: CAS: 2230821-27-7Chiralstar, Inc.Ships from: United StatesTo:TBD POA1 gDescription: CAS: 2230821-27-7For a custom pack size or bulk
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