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IUPAC Name: 
(3R)-1-[4,4-bis(3-methylthiophen-2-yl)(1,1,2,2,3-²H₅)but-3-en-1-yl]piperidine-3-carboxylic acid hydrochloride
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MedChemExpress
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1 mg
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Description: Names: Tiagabine-d5 (hydrochloride); NO050328-d5 (hydrochloride); NO328-d5 (hydrochloride); TGB-d5 (hydrochloride); Product Description: Tiagabine-d5 (hydrochloride) is deuterium labeled Tiagabine (hydrochloride). Tiagabine hydrochloride (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease; Target: GABA Receptor;Isotope-Labeled Compounds; CAS: 1253297-72-1
MedChemExpress EU
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Description: Names: Tiagabine-d5 (hydrochloride); NO050328-d5 (hydrochloride); NO328-d5 (hydrochloride); TGB-d5 (hydrochloride); Product Description: Tiagabine-d5 (hydrochloride) is deuterium labeled Tiagabine (hydrochloride). Tiagabine hydrochloride (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease; Target: GABA Receptor;Isotope-Labeled Compounds; CAS: 1253297-72-1
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Zoom the structure CSCS20620705730 Add to cart
IUPAC Name: 
(3R)-1-{4,4-bis[3-(²H₃)methylthiophen-2-yl]but-3-en-1-yl}piperidine-3-carboxylic acid hydrochloride
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Targetmol Chemicals Inc
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30 days 395.00
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Description: Tiagabine-D6 hydrochloride is intended for use as an internal standard for the quantification of tiagabine by GC- or LC-MS. Tiagabine is an inhibitor of GABA transporter 1. It inhibits seizures induced by DMCM in mice. Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8 µmol/kg, and it acts synergistically with gabapentin to delay pain responses in mice in the hot plate test. Formulations containing tiagabine have been used as adjunctive therapies in the treatment of partial seizures.; CAS: 1217808-68-8
MedChemExpress
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Description: Names: Tiagabine-methyl-d6 (hydrochloride); Product Description: Tiagabine-methyl-d6 (hydrochloride) is the deuterium labeled Tiagabine-methyl hydrochloride; Target: Isotope-Labeled Compounds; CAS: 1217808-68-8
MedChemExpress EU
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450.00
1 mg
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Description: Names: Tiagabine-methyl-d6 (hydrochloride); Product Description: Tiagabine-methyl-d6 (hydrochloride) is the deuterium labeled Tiagabine-methyl hydrochloride; Target: Isotope-Labeled Compounds; CAS: 1217808-68-8
Toronto Research Chemicals
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50 days 260.70
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Description: Tiagabine-methyl-d6 Hydrochloride; Storage Condition: -20°C; CAS: 1217808-68-8
Alfa Chemistry Analytical Products
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7 days
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1 g
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Description: CAS: 1217808-68-8
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Zoom the structure CSCS00159258039 Add to cart
IUPAC Name: 
(3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]piperidine-3-carboxylic acid hydrate hydrochloride
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1st Scientific EU
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30 days 179.30
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Description: Tiagabine hydrochloride monohydrate; CAS: 145821-57-4
1st Scientific LLC
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30 days 179.30
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Description: Tiagabine hydrochloride monohydrate; CAS: 145821-57-4
BLD Pharmatech Co., Limited
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30 days
200.00
50 mg
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Description: Name:(R)-1-(4,4-Bis(3-methylthiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride hydrate; CAS: 145821-57-4
BLD Pharmatech GmbH
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30 days
200.00
50 mg
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Description: Name:(R)-1-(4,4-Bis(3-methylthiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride hydrate; CAS: 145821-57-4
Targetmol Chemicals Inc
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30 days 2,140.00
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Description: Tiagabine hydrochloride hydrate is a potent and selective inhibitor of GABA uptake, inhibiting [3H] GABA uptake in synaptosomes, neurons, and glia with IC50 values of 67, 446, and 182 nM, respectively. This hydrate can be used as an anticonvulsant.; CAS: 145821-57-4
10X CHEM
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Description: Tiagabine hydrochloride monohydrate; CAS: 145821-57-4
Angene International Limited
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TBD
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1 g
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Description: CAS: 145821-57-4
Angene US
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Description: CAS: 145821-57-4
MedChemExpress
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1 mg
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Description: Names: Tiagabine hydrochloride hydrate; NO050328 hydrochloride hydrate; NO328 hydrochloride hydrate; TGB hydrochloride hydrate; Product Description: Tiagabine (NO050328; NO328; TGB) hydrochloride hydrate is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride hydrate exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride hydrate is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease; Target: GABA Receptor; CAS: 145821-57-4
MedChemExpress EU
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TBD
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1 mg
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Description: Names: Tiagabine hydrochloride hydrate; NO050328 hydrochloride hydrate; NO328 hydrochloride hydrate; TGB hydrochloride hydrate; Product Description: Tiagabine (NO050328; NO328; TGB) hydrochloride hydrate is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride hydrate exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride hydrate is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease; Target: GABA Receptor; CAS: 145821-57-4
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Zoom the structure CSCS03437848297 Add to cart
IUPAC Name: 
(3R)-1-(3-{tricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)piperidine-3-carboxylic acid hydrochloride
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1st Scientific EU
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30 days 559.90
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Description: ReN-1869 hydrochloride; CAS: 170149-76-5
1st Scientific LLC
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30 days 559.90
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Description: ReN-1869 hydrochloride; CAS: 170149-76-5
Targetmol Chemicals Inc
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30 days 1,520.00
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Description: ReN 1869 hydrochloride is a novel and selective histamine H1 receptor antagonist.; CAS: 170149-76-5
10X CHEM
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Description: ReN-1869 hydrochloride; CAS: 170149-76-5
Angene International Limited
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TBD
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1 g
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Description: ReN-1869 hydrochloride; CAS: 170149-76-5
Angene US
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TBD
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Description: ReN-1869 hydrochloride; CAS: 170149-76-5
MedChemExpress
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Description: Names: ReN-1869 hydrochloride; NNC-05-1869 hydrochloride; Product Description: ReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0.19±0.04 μM and the non-selective σ site (guinea pig brain) with Ki of 0.45 μM.; Target: Histamine Receptor; CAS: 170149-76-5
MedChemExpress EU
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Description: Names: ReN-1869 hydrochloride; NNC-05-1869 hydrochloride; Product Description: ReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0.19±0.04 μM and the non-selective σ site (guinea pig brain) with Ki of 0.45 μM.; Target: Histamine Receptor; CAS: 170149-76-5
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Zoom the structure CSCS02495325715 Add to cart
IUPAC Name: 
ethyl (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]piperidine-3-carboxylate hydrochloride
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10X CHEM
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1 g
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Description: 3-Piperidinecarboxylic acid, 1-[4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl]-, ethyl ester, hydrochloride (1:1), (3R)-; CAS: 145821-60-9
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Zoom the structure CSCS21399450482 Add to cart
IUPAC Name: 
3-{1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl} 5-methyl (2R,3S,4R,5R,6S)-2,6-dimethyl-4-(3-nitrophenyl)piperidine-3,5-dicarboxylate hydrochloride
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Elsa Biotechnology Co.,Ltd.
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1 g
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Description: CAS: 132866-11-6
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Zoom the structure CSCS03547006375 Add to cart
IUPAC Name: 
(4R,5R,7S,8R,9S,11S,13E,15R,18S,21R)-18-[(2S,3S,4E)-5-[(1R,3R,4S)-4-chloro-3-methoxycyclohexyl]-3-hydroxy-4-methylpent-4-en-2-yl]-15-ethyl-4-hydroxy-7,9-dimethoxy-5,11,13-trimethyl-19,26-dioxa-1-azatricyclo[19.3.1.1⁴,⁸]hexacos-13-ene-2,3,16,20-tetrone
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MedChemExpress
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Description: Names: Pimecrolimus impurity 3; iso-Pimecrolimus; Product Description: Pimecrolimus impurity 3 (iso-Pimecrolimus) is an impurity of Pimecrolimus.; Target: Drug Intermediate
MedChemExpress EU
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Description: Names: Pimecrolimus impurity 3; iso-Pimecrolimus; Product Description: Pimecrolimus impurity 3 (iso-Pimecrolimus) is an impurity of Pimecrolimus.; Target: Drug Intermediate
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Zoom the structure CSCS21346043797 Add to cart
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