With 516 approved drugs and counting, G-protein coupled receptors (GPCRs) account for a massive 36% of all approved therapeutics. In 2023 alone, GPCR-targeting drugs for diabetes and obesity hit $30 billion in global sales. As clinical trials surge in metabolic diseases, oncology, and immunology, GPCRs continue to be one of the most powerful and promising families in pharma.

At Chemspace, we are keeping up the pace.

Our team has designed a GPCR Targeted Library using USRCAT-based ligand similarity, bringing together 112,000+ diverse compounds predicted to act on 182 targets across 65 GPCR families.

Explore the library:

https://chem-space.com/compounds/gpcrs-targeted-library

Can’t find your target? No problem - we offer custom library design based on your needs. Just reach out!