News and Events

Phenotypic screening (PS) is one of the two major approaches at early stage drug discovery projects, apart from the target-based screens. PS is focused on the overall effect a drug molecule causes in the cell rather than an effect found for a single target. To create Chemspace PS library, we have selected the compounds with activity annotations in ChEMBL from Chemspace Screening Compound set. Compounds have favorable physicochemical profiles. PAINS and toxic molecules have been removed. Each molecule is annotated with UniProt codes list of reported targets. Please use the link to download the set: https://bit.ly/2STV7cS or browse others Chemspace compound sets: https://lnkd.in/ddVRtBJ Also, our Summer Sale is on – order now, pay later, and save up to 15%!

In August 2018, FDA approved PIFELTRO (doravirine) as a HIV-1 infection drug. It contains 1,2,4-triazolone moiety in its backbone. This fact could not pass unnoticed. That is why we have prepared a set of 77 1,2,4-triazolones and their nearest derivatives to power up your research. 

Dear colleagues! We are looking forward to seeing you at the 258th ACS National Meeting & Exposition in August!

Molecules of the week are back! This time we would like to point at Saturated Aminonitriles. We at ChemSpace always have new small molecules to power up your research.

We are happy to annouce mega summer sale on all of our Compond Sets.

You can save up to 15%! Please use this link to browse through our Fragments, Screening Compounds, Building Blocks Compound Sets or contact us sales@chem-space.com to create a unique set only for you!

Visit our page of compound libraries to explore ALL of our Compound Sets!

To browse ALL our compound sets, please use this link: https://chem-space.com/compounds.

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized.

Compound Sets sale is coming soon! Please follow the updates. This summer is going to be special...

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized. https://bit.ly/2VKiomb

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. 

Chemspace and Molecular Forecaster Announce Partnership Streamlining Early Drug Discovery by Linking Chemical Design, Purchasing, and Modeling.

Chemspace offers high quality Building Blocks suitable as cores and as decorators for DEL. Compounds have favorable PhysChem profiles.

Beta-amino acids have been promising building blocks as they often provide potency and stability to the molecules. We have prepared a set of beta-amino acids to power up your research.

Chemspace is by far the largest database of small molecules to search and buy. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from our database.

Discover Chemspace Tiny Fragments – a library of PAINS- and undesirable reactivity-free compounds that have 5-8 heavy atoms. To browse other compound libraries please go to Compound Sets Page.

Amino acids are a class of chemical compounds important for many chemistry-based research projects. The applications vary from peptide synthesis to fragment-based screening and from docking studies to simply next-step molecule optimization. Nevertheless, finding a source offering a range of in-stock and synthetically feasible compounds, available for search and purchase has always been a challenge. Most online chemical databases promise a little when talking about synthesis of interested compound that is not in stock. So what options does a research chemist have? Chemspace! At Chemspace, we provide over 1.5 million of amino acids on your demand establishing a great source for your research needs! In addition, Boc/Fmoc/Alloc/Cbz-protected derivatives as well as amino acid esters are also available. 

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized. 

Last week we added the Expanded Space search option. Now, Chemspace users can access over 800 million molecules database to find new ideas for their research! Using Substructure or Similarity search returns you up to 1,000 similars to your query in just a few seconds. Once found, you can inquire any molecule from the results list. So, please go ahead and try our this new search option. Should you have any question just let us know.

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized. 

Meet us at the 14th Annual Drug Discovery Chemistry! April 8-12th. San Diego Convention Center. 

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized. 

Today we would like to focus your attention on the tremendously versatile out of a number of those: aziridines. We have prepared a set of 1215 azeridines to power up your research.

Chemspace is by far the largest database of small molecules to search and buy. We offer you a huge number of off-the-shelf compounds provided by world-known suppliers. You, however, can expand the capabilities to design your molecules with make-on-demand analogs from the Chemspace database. Over 90% of our make-on-demand offering includes molecules that could be easily accessed from available reagents via optimized procedures and not custom-synthesized. 

We hate teasers, but still: search in Expanded Chemical Space (almost in 1 Billion molecules) will soon be available online on Chem-space.com, please follow the news. Please visit www.chem-space.com to search in 100 million building blocks, fragments, and screening compounds.