News and Events

Dear friends and colleagues!

Thanks to everyone for joining the  Chemspace & AnalytiCon Discovery Webinar 'Unique Chemical Space Covered by 3D Synthetic Chemistry: Beyond Ro5' yesterday!

For those who didn’t have a chance to connect, the recording is already available!

We are happy to introduce our new video series - Chemspace Tutorials.

Enjoy the Pilot!

https://youtu.be/hBrtZKlIgkk

Dear friends and colleagues!

Join Chemspace & AnalytiCon Discovery Webinar 'Unique Chemical Space Covered by 3D Synthetic Chemistry: Beyond Ro5', which will take place TOMORROW (April 29th, 2021) at 5:00 PM (CET) / 8:00 AM (PST).

The Speaker is Dr. Dietmar Wolf, Executive Vice President of AnalytiCon Discovery.

Register via the link now!

We are happy to continue our new inspired by Drug Hunter’s “Small Molecules of the Month” series!

Here are three molecules that were recently highlighted by Drug Hunter!

Last July, a group of researchers published a Review that highlighted several approaches addressed to overcome chemotype-specific resistance to inhibitors in anticancer treatment.

Targeting multiple binding pockets or allosteric binding sites and designing inhibitors with distinct binding modes are among such strategies. The two next approaches are targeted degradation using PROteolysis Targeting Chimeras (PROTACs) and cysteine-targeting covalent inhibitors.

We at Chemspace offer you sets with Covalent Fragments and Covalent Modifiers!

Dear friends and colleagues!

Join our second Chemspace & AnalytiCon Discovery Webinar 'Leveraging Natural Product-based Chemical Spaces', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on May 11th, 2021.
The Speaker is Dr. Lars Ole Haustedt, Director Projects & Innovation at AnalytiCon Discovery.

Register via the link now!

Dear friends and colleagues!

With a new version of DataWarrior you can get even more from the tool: search in Chemspace database!

Now the largest catalog available to search in DataWarrior!

https://youtu.be/0ypIiaDMQYk

Please visit chem-space.com if you want to source these compounds!

Trifunctional Aromatic Acids are the Molecules of This Week.

We at Chemspace always have new small molecules to power up your research.

To browse the set please use the link!

This March, Ponesimod (PONVORY) received approval by the FDA for the treatment of patients with relapsing forms of multiple sclerosis (MS). It is one of four sphingosine-1-phosphate (S1P) receptor modulators that bind selectively to S1P1 receptors, identified in having a pivotal role in the regulation of lymphocyte trafficking in MS.

Ponesimod contains 1,3-thiazolidine moiety in its backbone.

We have made a set of Building Blocks, which contain 1,3-thiazolidine parts – the perfect start for your research!

Dear friends and colleagues!

Join Chemspace & AnalytiCon Discovery Webinar 'Unique Chemical Space Covered by 3D Synthetic Chemistry: Beyond Ro5', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on April 29th, 2021.

The Speaker is Dr. Dietmar Wolf, Executive Vice President of AnalytiCon Discovery.

Register via the link now!

Dear friends and colleagues!

Thanks to everyone for joining the  Chemspace & CrystalsFirst Webinar 'How to optimize the fragment hit rate: take protein crystals first' yesterday!

For those who didn’t have a chance to connect, the recording is already available!

Dear friends and colleagues!

Join Chemspace & CrystalsFirst Webinar 'How to optimize the fragment hit rate: take protein crystals first', which will take place TOMORROW (April 13th, 2021) at 5:00 PM (CET) / 8:00 AM (PST).

Register via this link now!

Last year, a group of researchers from Google Research Applied Science and X-Chem, published an article that describes an effective approach for hit finding using Machine Learning (ML) based on DNA-Encoded Libraries (DEL). The authors demonstrate how ML could be applied to DEL selection data by identifying active molecules from large libraries of commercial and tangible compounds.

Chemspace inspires You to start new projects using DEL and we offer Blocks for creating DELs and Ready to use self-serve product from HitGen Inc. - OpenDEL®!

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for March in case you have missed them!

Spiro Thiols are the Molecules of This Week.

We at Chemspace always have new small molecules to power up your research.

To browse the set please use the link!

Dear friends and colleagues!

Join Chemspace & CrystalsFirst Webinar 'How to optimize the fragment hit rate: take protein crystals first', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on April 13th, 2021.

Register via this link now!

Happy Easter!

Let's celebrate with hope, love, and good health!

Stay safe!

Your Chemspace Team.

New version of Enamine REAL Space is now searchable through Chemspace!

You can access 17.7 Billion molecules here!
Many thanks to Enamine (https://www.enamine.net) for creating the largest synthetically accessible space and BioSolveIT (https://www.biosolveit.de) for developing an incredible search tool!

In 2020, a group of researchers from University of Michigan published a Viewpoint that describes an approaches to mitigate aniline-related toxicities of drugs and drug candidates with the help of saturated isosteres of aniline.

The authors showed that the great part of drugs with idiosyncratic adverse drug reactions (IADRs) were caused by aniline bioactivation and reactive metabolite (RM) formation.

We at Chemspace have selected sets with derivatives of these four bioisosteres of aniline - aminoBCP, aminoBCO, aminoCUB, aminoNB.

We are happy to continue our new inspired by Drug Hunter’s “Small Molecules of the Month” series!

Here are two molecules which were recently highlighted by Drug Hunter!

Halogenated Heteroaromatic Carboxylic Acids are the Molecules of This Week.

We at Chemspace always have new small molecules to power up your research.

To browse the set please use the link!

Thanks everyone for joining the Chemspace & Bienta Webinar ‘From Chemistry to Biology in less than one week’ yesterday!

For those who didn’t have a chance to connect, the recording is already available!

Dear friends and colleagues!

Join the Chemspace & Bienta Webinar ‘From Chemistry to Biology in less than one week’, which will take place at 5:00 PM (CET) / 9:00 AM (PST) TOMORROW (March, 18)!

New semester has begun, to support the researchers and students’ research after a long-time interrupt by the pandemic, TargetMol is releasing a new marketing promotion.

Dear friends and colleagues!

Join the Chemspace & Bienta Webinar ‘From Chemistry to Biology in less than one week’, which will take place at 5:00 PM (CET) / 9:00 AM (PST) on March, 18.