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  • Building Blocks for Analogs of CRN04894

    Discover key analog molecules for fragments of a potential drug such as CRN04894, a promising treatment for Cushing syndrome in the last issue of the "Building Blocks for Drug Candidates" series. Find them here.

  • Chemspace Monthly Digest. April 2024

    We are summarizing the latest updates from Chemspace. Check out our April post roundup!

  • Building Blocks for Analogs of Danicopan!

    In March, the FDA approved Danicopan (Voydeya®) for treating chronic, progressive and potentially life-threatening blood disorder. This drug's backbone includes a 3-fluoropyrrolidine moiety. Explore 3-fluoropyrrolidine-based compounds for your research! 

  • Novel method of fragment growing!

    Growing fragments into lead compounds has never been simpler with our REAL Fragment Pre-Plated Library! Learn more here.

  • The ChEMBL analogs collection is updated!

    With the release of ChEMBL 34, we are thrilled to announce that our ChEMBL analogs collection has been updated as well! Click here to discover our ChEMBL analogs.

  • Our latest webinar is now live on YouTube!

    Our latest webinar with AlphaMa on 'Intelligent application of DNA-encoded libraries' is now live on the Chemspace YouTube channel!

  • Analogs to New Biological Tool Compounds

    We bring you a new post in our series inspired by Drug Hunter's "Molecules of the Month"!

    A recently highlighted molecule is AZD5462 - a therapeutic candidate recently identified by Drug Hunter, which is a powerful and specific pharmacological mimic of relaxin H2 signaling that could be used to treat heart failure.

  • 35th Symposium on Medicinal Chemistry

    Meet Rita Gaidar at the 35th Symposium on Medicinal Chemistry in Eastern England on April 25th. Looking forward to exploring partnership opportunities!

  • Join the Chemspace & AlphaMa Webinar TOMORROW!

    Do not miss a chance to join our webinar, which will take place tomorrow at 3 pm CET | 9 am EDT | 9 pm CST (Beijing time)! Register via the link.

  • Biologics for Research – Methionine adenosyltransferase 2A

    Explore a selected Biological Products Set from Chemspace for studying Methionine adenosyltransferase 2A (MAT2A) pathways, crucial in different kinds of cancer. Follow the link to check out the comprehensive selection at Chemspace Biologics! 

  • Building Blocks for Analogs of Cilofexor

    Check out our new series: "Building Blocks for Drug Candidates"! Discover essential sets for synthesizing potential drugs like Cilofexor, a promising treatment for primary sclerosing cholangitis.

  • Join the Chemspace & AlphaMa Webinar!

    Join our webinar “Intelligent Applications of DNA-Encoded Chemical Libraries”, which will take place at 3 pm CET on April 18th, 2024. 

     

  • Meet our team at EFMC-ASCMEDI Medicinal Chemical Frontiers 2024!

    Meet Chemspace team at EFMC-ASCMEDI Medicinal Chemical Frontiers 2024, taking place from April 8-11 in Utrecht, the Netherlands. 

  • Chemspace Monthly Digest. March 2024

    We are summarizing the latest updates from Chemspace. Check out our March post roundup!

  • Our new product – REAL Fragment Library!

    Meet our new product – REAL Fragment Library! Discover the new efficient method of fragment growing inside Enamine REAL space.

  • Meet Chemspace Team – Junior Backend Developer Dmytro Yehorov!

    Today we would like you to meet our Junior Backend Developer - Dmytro Yehorov. Follow the link to get to know him better!

  • A new Chemspace featured article is out!

    Check out our latest featured article where researchers utilized the next generation SpaceProp2 analysis tool to explore Freedom Space.

  • Meet our team at the Drug Discovery Chemistry Conference 2024!

    Meet Olga Tarkhanova and Olena Strapak at the Drug Discovery Chemistry Conference in San Diego on April 1-4, 2024!

  • A new Chemspace co-authored article is out!

    Congratulations to Olga Tarkhanova, and Mykola Protopopov, on their new article dedicated to the application of the fragment-based approach to discover a new PYCR1 inhibitor. Read more about their groundbreaking research here.

  • PharmAI Collaboration – AI-supported focused library

    We are thrilled to announce our new product, developed in partnership with PharmAI – 1400 AI-Supported Focused Library!

  • Chemspace team in Munich!

    We are at Frontiers in Medicinal Chemistry 2024 in Munich! Do not miss the chance to meet our experts Olena Strapak and Anna Kapeliukha at poster board #45!

  • Biologics for Research – Glucocorticoid Receptors (GRs)

    Explore a selected set of over 230 Biologics from Chemspace for studying Glucocorticoid receptors (GRs), pivotal in regulating metabolism, inflammation, and the immune response. Follow the link to check out the comprehensive selection at Chemspace Biologics!

  • Meet our team at the Frontiers in Medicinal Chemistry Conference!

    Meet Olena Strapak and Anna Kapeliukha in Munich, Germany at the Frontiers in Medicinal Chemistry Conference, March 17-20!

  • Building Blocks for DEL. Part 4. Boc-Hydrazines

    Introducing our newest addition to the 'Novel DEL-compatible Building Blocks' series! Our Boc-hydrazines, with over 300 compounds ready in just 3-4 weeks, offer bench-stable reliability and precise regioselectivity for your DEL synthesis needs.

  • Analogs to New Biological Tool Compounds

    We bring you a new post in our series inspired by Drug Hunter's "Molecules of the Month"!

    A recently highlighted molecule is MZ-101 - an oral and selective GYS1 inhibitor that decreases glycogen accumulation in skeletal muscle, potentially offering a treatment for Pompe disease.

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