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IUPAC Name: 
1-{2-[3-(2-{[5-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)pentyl]oxy}ethoxy)propanamido]-3,3-dimethylbutanoyl}-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
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Molnova Chemicals
Ships from: United States
To:
10 days 64
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Description: Gefitinib-based PROTAC 3; CAS: 2230821-27-7
Angel Pharmatech Ltd.
Ships from: China
To:
10 days 435
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Description: CAS: 2230821-27-7
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Zoom the structure CSSB02515421219 Add to cart
IUPAC Name: 
5-(19-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-19-oxo-4,7,10,13,16-pentaoxa-1-azanonadecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
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Enamine Ltd
Ships from: Ukraine
To:
5 days 104
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MedChemExpress
Ships from: United States
To:
10 days
480
5 mg
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Description: Names: MS9427; Product Description: MS9427 is a potent PROTAC EGFR degrader with K d s of 7.1 nM and 4.3 nM for EGFR WT and EGFR L858R, respectively. MS9427 selectively degrades the mutant but not the WT EGFR through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9427 potently inhibits the proliferation of NSCLC cells. MS9427 can be used for researching anticancer .; Target: EGFR;PROTACs; CAS: 2772613-37-1
MedChemExpress EU
Ships from: Sweden
To:
10 days
506
5 mg
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Description: Names: MS9427; Product Description: MS9427 is a potent PROTAC EGFR degrader with Kds of 7.1 nM and 4.3 nM for EGFR WT and EGFR L858R, respectively. MS9427 selectively degrades the mutant but not the WT EGFR through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9427 potently inhibits the proliferation of NSCLC cells. MS9427 can be used for researching anticancer; Target: EGFR;PROTACs; CAS: 2772613-37-1
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Zoom the structure CSSS06657276019 Add to cart
IUPAC Name: 
5-(19-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-19-oxo-4,7,10,13,16-pentaoxa-1-azanonadecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione; trifluoroacetic acid
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MedChemExpress
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10 days 480
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Description: Names: MS9427 (TFA); Product Description: MS9427 TFA is a potent PROTAC EGFR degrader with K d s of 7.1 nM and 4.3 nM for EGFR WT and EGFR L858R, respectively. MS9427 TFA selectively degrades the mutant but not the WT EGFR through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9427 TFA potently inhibits the proliferation of NSCLC cells. MS9427 TFA can be used for researching anticancer .; Target: EGFR;PROTACs
MedChemExpress EU
Ships from: Sweden
To:
10 days 506
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Description: Names: MS9427 (TFA); Product Description: MS9427 TFA is a potent PROTAC EGFR degrader with Kds of 7.1 nM and 4.3 nM for EGFR WT and EGFR L858R, respectively. MS9427 TFA selectively degrades the mutant but not the WT EGFR through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9427 TFA potently inhibits the proliferation of NSCLC cells. MS9427 TFA can be used for researching anticancer; Target: EGFR;PROTACs
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Zoom the structure CSSS06744597657 Add to cart
IUPAC Name: 
1-({4-[(2S)-5-(carbamoylamino)-2-[(2S)-2-[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido]-3-methylbutanamido]pentanamido]phenyl}methyl)-4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-1-ium chloride
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MedChemExpress EU
Ships from: Sweden
To:
10 days 490
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Description: Names: Mc-Val-Cit-PAB-Gefitinib (chloride); Product Description: Mc-Val-Cit-PAB-Gefitinib chloride is a agent-linker conjugates for ADC. Mc-Val-Cit-PAB-Gefitinib chloride consists of Gefitinib (HY-50895) (an EGFR tyrosine kinase inhibitor) and the ADC linker Mc-Val-Cit-PAB; Target: Drug-Linker Conjugates for ADC
MedChemExpress
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To:
10 days 570
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Description: Names: Mc-Val-Cit-PAB-Gefitinib (chloride); Product Description: Mc-Val-Cit-PAB-Gefitinib chloride is a agent-linker conjugates for ADC . Mc-Val-Cit-PAB-Gefitinib chloride consists of Gefitinib (HY-50895) (an EGFR tyrosine kinase inhibitor) and the ADC linker Mc-Val-Cit-PAB .; Target: Drug-Linker Conjugates for ADC
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Zoom the structure CSSS06744597765 Add to cart
IUPAC Name: 
(2S,4R)-1-[(2S)-2-(11-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-11-oxoundecanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
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BLD Pharmatech Co., Limited
Ships from: United States
To:
1 day 273
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Description: Name:(2S,4R)-1-((S)-2-(11-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-11-oxoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CAS: 2675490-92-1
BLD PHARMATECH LTD CN
Ships from: China
To:
7 days 153
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Description: Name:(2S,4R)-1-((S)-2-(11-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-11-oxoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CAS: 2675490-92-1
A2B Chem
Ships from: United States
To:
12 days 544
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Description: MS 39; CAS: 2675490-92-1
Angene US
Ships from: United States
To:
15 days 751
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Description: MS 39; CAS: 2675490-92-1
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Zoom the structure CSSB14855342050 Add to cart
IUPAC Name: 
(2S,4R)-1-[(2S)-2-(11-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-11-oxoundecanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
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MedChemExpress
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To:
10 days 200
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Description: Names: MS39; Product Description: MS39 (compound 6) is a PROTAC targeting EGFR . MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells .; Target: EGFR;PROTACs; CAS: 2675490-92-1
MedChemExpress EU
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To:
10 days 211
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Description: Names: MS39; Product Description: MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells; Target: EGFR;PROTACs; CAS: 2675490-92-1
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Zoom the structure CSSS14855342050 Add to cart
CAS: 2772612-96-9
IUPAC Name: 
(3S)-N-(11-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-11-oxoundecyl)-3-{[(2S,4R)-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-1,2-oxazol-5-yl)butanoyl]pyrrolidin-2-yl]formamido}-3-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]propanamide
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A2B Chem
Ships from: United States
To:
12 days 735
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Description: MS9449; CAS: 2772612-96-9
Angene US
Ships from: United States
To:
15 days 1,004
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Description: MS9449; CAS: 2772612-96-9
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Zoom the structure CSSB06741697602 Add to cart
CAS: 2772612-96-9
IUPAC Name: 
(3S)-N-(11-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-11-oxoundecyl)-3-{[(2S,4R)-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-1,2-oxazol-5-yl)butanoyl]pyrrolidin-2-yl]formamido}-3-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]propanamide
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MedChemExpress
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To:
10 days 540
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Description: Names: MS9449; Product Description: MS9449 is a potent PROTAC EGFR degrader with K d s of 17 nM and 10 nM for EGFR WT and EGFR L858R, respectively. MS9449 effectively induces degradation of mutant EGFRs through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9449 potently inhibits the proliferation of NSCLC cells. MS9449 can be used for researching anticancer .; Target: EGFR;PROTACs; CAS: 2772612-96-9
MedChemExpress EU
Ships from: Sweden
To:
10 days 569
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Description: Names: MS9449; Product Description: MS9449 is a potent PROTAC EGFR degrader with Kds of 17 nM and 10 nM for EGFR WT and EGFR L858R, respectively. MS9449 effectively induces degradation of mutant EGFRs through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9449 potently inhibits the proliferation of NSCLC cells. MS9449 can be used for researching anticancer; Target: EGFR;PROTACs; CAS: 2772612-96-9
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Zoom the structure CSSS06741697602 Add to cart
IUPAC Name: 
6-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)-N-{2-[(1-{2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethyl}-1H-1,2,3-triazol-4-yl)methoxy]-1-{[6-(4-{2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoyl}piperazin-1-yl)-6-oxohexyl]carbamoyl}ethyl}hexanamide
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MedChemExpress
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10 days 850
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Description: Names: DP-C-4; Product Description: DP-C-4 is a Cereblon -based dual PROTAC for simultaneous degradation of EGFR and PARP .; Target: EGFR;PARP;PROTACs
MedChemExpress EU
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To:
10 days 896
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Description: Names: DP-C-4; Product Description: DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP; Target: EGFR;PARP;PROTACs
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Zoom the structure CSSS06256034989 Add to cart
CAS: 153436-53-4
IUPAC Name: 
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
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Angene US
Ships from: United States
To:
5 days 56
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Description: CAS: 153436-53-4
Selleck Chemicals GmbH
Ships from: Germany
To:
10 days 87
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Description: CAS: 153436-53-4
StruChem CO., LTD
Ships from: China
To:
10 days
609
1 g
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Description: CAS: 153436-53-4
ChemShuttle
Ships from: United States
To:
28 days 330
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Toronto Research Chemicals
Ships from: Canada
To:
50 days 103
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Description: Tyrphostin AG 1478; Storage Condition: 4°C; CAS: 175178-82-2
Molnova Chemicals
Ships from: United States
To:
TBD 45
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Description: AG-1478; CAS: 153436-53-4
LEAP CHEM Co., Ltd.
Ships from: China
To:
15 days
POA
1 g
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Description: AG-1478 (Tyrphostin AG-1478); CAS: 153436-53-4
Shanghai Mathcon Pharmaceutical Co.,LTD.
Ships from: China
To:
28 days
POA
1 g
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Description: CAS: 153436-53-4
RR Scientific LLC
Ships from: United States
To:
30 days
POA
1 g
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Description: CAS: 153436-53-4
Alfa Chemistry Analytical Products
Ships from: United States
To:
TBD
POA
1 g
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Apollo Scientific USA
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 153436-53-4
BOC Sciences
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 153436-53-4
Chiralstar, Inc.
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 153436-53-4
Crysdot LLC
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 153436-53-4
HDH Pharma Inc
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 175178-82-2
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Zoom the structure CSCS00015190316 Add to cart
CAS: 170449-18-0
IUPAC Name: 
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
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Angene US
Ships from: United States
To:
5 days 9
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Description: 6,7-Dimethoxy-4-[N-(3-chlorophenyl)amino]quinazoline hydrochloride; CAS: 170449-18-0
Angel Pharmatech Ltd.
Ships from: China
To:
20 days
562
1 g
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Description: CAS: 170449-18-0
MedChemExpress
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30 days 55
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Description: Names: AG-1478 (hydrochloride); Tyrphostin AG-1478 (hydrochloride); NSC 693255 (hydrochloride); Product Description: AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC 50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV) .; Target: EGFR;HCV;Influenza Virus; CAS: 170449-18-0
MedChemExpress EU
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To:
30 days 58
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Description: Names: AG-1478 (hydrochloride); Tyrphostin AG-1478 (hydrochloride); NSC 693255 (hydrochloride); Product Description: AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV); Target: EGFR;HCV;Influenza Virus; CAS: 170449-18-0
Advanced ChemBlock Inc
Ships from: United States
To:
30 days
165
1 g
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Description: 6,7-Dimethoxy-4-[N-(3-chlorophenyl)amino]quinazoline hydrochloride; CAS: 170449-18-0
LEAP CHEM Co., Ltd.
Ships from: China
To:
15 days
POA
1 g
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Description: AG 1478 hydrochloride; CAS: 170449-18-0
RR Scientific LLC
Ships from: United States
To:
30 days
POA
1 g
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Description: CAS: 170449-18-0
Alfa Chemistry
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 170449-18-0
Alichem
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 170449-18-0
BOC Sciences
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 170449-18-0
Crysdot LLC
Ships from: United States
To:
TBD
POA
1 g
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Description: CAS: 170449-18-0
Targetmol Chemicals Inc
Ships from: United States
To:
TBD
POA
1 mg
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Description: AG1478 HCl is an epidermal growth factor receptor protein inhibitor.; CAS: 170449-18-0
Zerenex Molecular Ltd
Ships from: United Kingdom
To:
TBD
POA
1 g
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Description: CAS: 170449-18-0
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Zoom the structure CSCS00015191080 Add to cart
IUPAC Name: 
N-(3-chloro-2-methylphenyl)-6,7-dimethoxyquinazolin-4-amine
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BLD Pharmatech Co., Limited
Ships from: United States
To:
30 days
342
1 g
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Description: Name:N-(3-Chloro-2-methylphenyl)-6,7-dimethoxyquinazolin-4-amine; CAS: 477855-15-5
BLD Pharmatech GmbH
Ships from: Germany
To:
30 days
342
1 g
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Description: Name:N-(3-Chloro-2-methylphenyl)-6,7-dimethoxyquinazolin-4-amine; CAS: 477855-15-5
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Zoom the structure CSCS00138418408 Add to cart
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