News and Events

Our todays’ review is focused on pyrrole and its hetero-fused derivatives with anticancer, antimicrobial, and antiviral activities.

A pyrrole-based compound set is waiting for you!
 

Meet Chemspace mascots! They will help us to guide you through the latest Chemspace news and plans. And we hope you`ll love them too!

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for October in case you have missed them!

We are looking forward to catching up with you in-person at CPhI Worldwide!
See up!

Halogenated Benzaldehydes are the Molecules of the Month!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

If you haven`t found your target in our library, our computational chemistry services team is ready to help you to create a custom one! For the full list of services write at [email protected].

This September, Atogepant received approval by the FDA as a drug for the treatment of episodic migraine.

It is an oral calcitonin gene-related peptide (CGRP) receptor antagonist.

Atogepant contains aminopiperidinone moiety in its backbone.

We have made a set of Building Blocks, which contain such parts – the perfect start for your research!

Today we are proud to reveal GPCRs Targeted Library – an amazing new product, prepared by our computational chemistry services team.

590K+ compounds against 192 targets are waiting for you here!

The article we want to share today shows, that now it is possible to obtain high-quality 3D reconstructions by cryo-EM without the need for a stabilizing nanobody and with reduced cost.

Dear friends and colleagues!

Join the Chemspace Webinar 'Fast Structure-Based Virtual Screening in Readily Available Chemical Space of >10 Billion Compounds', which will take place at 5:00 PM (CET) / 8:00 AM (PST) TOMORROW, on October 21st, 2021.

The Speaker is Dr. Vsevolod Katritch, Assoc. Professor at the University of Southern California.

Register now via the link!

We are continuing our series of posts on GPCRs!

Determination of GPCRs structures is highly important for classification and SBDD on these targets. This thought is the key point of today’s highlighted article.

We are starting our GPCR information week with a nice review on GPCRomics – its approaches, gaps in knowledge, and future directions.

This year a group of scientists summarized the biological activity of thiazole and oxazole derivatives. We thought this is a great idea to provide you with two compound sets based on it!

Chemspace Catalog is already updated!
This means that now you are able to search in more than 4.3 Billion molecules!

So don’t waste your time and go check out the new compound choices that might become the perfect fit for your research!

https://chem-space.com/search

Dear friends and colleagues!

Join the Chemspace Webinar 'Fast Structure-Based Virtual Screening in Readily Available Chemical Space of >10 Billion Compounds', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on October 21st, 2021.
The Speaker is Dr. Vsevolod Katritch, Assoc. Professor at the University of Southern California.

Register via the link now!

Our todays’ article is covering the topic, sincerely loved by medicinal chemists – 3D aliphatic molecules, more specifically – bridged pyrrolidines. And of course. we couldn`t forget about an amazing compound set!

We are presenting a great opportunity for your research projects today – a combination of DEL and Machine Learning. Watch the video to find out more!

Hetaryl Primary Amines are the Molecules of the Month!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for September in case you have missed them!

Acetylenes have been broadly exploited in drug discovery and development and today we want to share a review on them, paired with a great compound set by Chemspace!

We have something very exciting for you! We posted a new collection of more than 2100 in-stock compounds, selected on a pharmacological similarity base against 50 targets on our website. Go check it out!

Chemspace is proud to announce catalog update! Now you will be able to search in 2+ BILLION molecules.

Just last month a group of scientists published an article called ‘Hydroxamic Acid Derivatives: From Synthetic Strategies to Medicinal Chemistry Applications’. 
The authors cover the synthesis and introduction of hydroxamic acid groups to various substrates, as well as medicinal chemistry applications of such compounds. Besides that, they mention their physicochemical profile and mutagenicity information, which are important for Drug Discovery projects.  

We are happy to continue our series of posts, which are inspired by Drug Hunter’s “Small Molecules of the Month”!
Here are two molecules that were recently highlighted by Drug Hunter!

Dear friends and colleagues!

Thanks to everyone for joining the Chemspace & River Stone Bio ApS Webinar 'Improving characteristics of SM by enzymatic glycosylation'!

For those who didn’t have a chance to connect, the recording is already available!