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  • Building Blocks for Analogs of Maralixibat

    Last September, Maralixibat received approval by the FDA for the treatment of cholestatic pruritus associated with Alagille syndrome.

    It is a reversible inhibitor of ileal bile acid transporter (IBAT).

    Viloxazine contains 1,4-diazabicyclo[2.2.2]octane moiety in its backbone.

    We have made a set of Building Blocks, which contain such parts – the perfect start for your research!

  • Creating libraries of analogs - Chemspace Calls

    A new video by Chemspace team is out on our YouTube channel! It covers the process of creating a compound library using our website. You should definitely check it out!

  • Chemspace Advent calendar! Part 3

    Chemspace Advent – day three! Look, George even put his festive glasses on for today. He is 100% ready for Christmas and to share a new compound set with you.

  • Chemspace Advent calendar! Part 2

    Day 2 of our Chemspace Advent calendar! What do you think is hidden under that Christmas tree?

  • Chemspace announces collaboration with Cambridge Molecular!

    We are proud to announce our collaboration with Cambridge Molecular - a leading provider of machine learning and data science services for DNA-Encoded Libraries!

    Stay tuned for the following updates on our collaboration!

  • Chemspace Advent calendar! Part 1

    First day of Chemspace Advent calendar! Hurry up to see what`s inside!

  • Urea derivatives in Drug Discovery

    Today George found a great article on urea derivatives for you! The traditional compound set is also waiting for you!

  • Ion Channels Targeted Library is now out on the website!

    A new compound library based on USRCAT similarity is already out on our website – Ion Channels Targeted Library!

  • New Chemspace co-authored article and webinar recording!

    A new Chemspace co-authored article is out! If you’ve missed the webinar on this topic, the recording is already available!

  • Analogs to New Biological Tool Compounds - 10

    We are happy to continue our series of posts, which are inspired by Drug Hunter’s “Small Molecules of the Month”!
    Here are two molecules that were recently highlighted by Drug Hunter!

  • New Chemspace co-authored publication is out!

    New Chemspace co-authored publication is out! You should definitely check it out!

  • Morpholine as pharmacophore in medicinal chemistry

    George is here with a great review on morpholine derivatives and synthetic medicinal chemistry and SAR. The article and a new compound set are available!

  • Analogs to New Biological Tool Compounds - 9

    We are happy to continue our series of posts, which are inspired by Drug Hunter’s “Small Molecules of the Month”!
    Here are two molecules that were recently highlighted by Drug Hunter!

  • Synthesis and medicinal chemistry of benzodiazepines

    Todays’ topic is benzodiazepines - a diverse class of bicyclic heterocyclic molecules. The article and a new compound set are waiting for your attention!

  • Chemspace Monthly Digest. November

    Meet Chemspace Monthly Digest! 

    Here is a summary of all Chemspace news and highlights for November in case you have missed them!

  • Molecules of This Month are Sulfonamide Amines!

    Sulfonamide Amines are the Molecules of the Month!

    We at Chemspace always have new small molecules to power up your research.

    To browse the set please use this link.

  • Three Lead-Like Diversity Sets are now out on the website!

    Three Lead-Like Compound Libraries are now out on the website! Each set is comprised of 10 thousand diversified molecules and is available for download.

  • New Publications section is now available on the website!

    Today we are proud to show you a new section on our website – Publications. Here you can find out more about publications co-authored by Chemspace and publications featuring our company.

  • Macrocycles in DNA-encoded libraries

    DNA-encoded libraries can be utilized as a great tool for developing and screening macrocycles in Drug Discovery. Check out the article and the offers we prepared for you here!

  • Imidazo[1,2-b]pyridazines in medicinal chemistry

    George Spacey continues to work on our weekend series and today he is ready to present you an amazing review on imidazo[1,2-b]pyridazines and their biological activity. The traditional compound set is also waiting for you!

  • Building Blocks for Analogs of Viloxazine

    This April, Viloxazine received approval by the FDA  as an oral drug for the treatment of attention deficit hyperactivity disorder (ADHD) in children.

    It acts as a selective norepinephrine reuptake inhibitor (NRI).

    Viloxazine contains morpholine moiety in its backbone.

    We have made a set of Building Blocks, which contain such parts – the perfect start for your research!

     

  • NEW Chemspace Website tutorials are live!

    Three new Chemspace tutorial videos are already available on our YouTube channel! We try our best to guide you through the most important steps of interaction with our website.

  • Sulfoximines in medicinal chemistry

    Interest in sulfoximine chemistry has been greatly increased recently, and todays’ article is all about this topic. Chemspace also offers a great sulfoximine-containing compound set!

  • Chemspace is proud to present Protein Kinases Targeted Libraries!

    Chemspace is proud to present a new product – Protein Kinases Targeted Libraries! General and Allosteric compound libraries are waiting for your attention here!

  • Chemspace & Dr. Vsevolod Katritch Webinar. Recording

    Dear friends and colleagues!

     

    Thanks to everyone for joining the Chemspace Webinar with Dr. Vsevolod Katritch - 'Fast Structure-Based Virtual Screening in Readily Available Chemical Space of >10 Billion Compounds'!

    For those who didn’t have a chance to connect, the recording is already available!

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