News and Events

Aryl Halides are the Molecules of This Week! We at Chemspace always have new small molecules to power up your research. To browse the set please use this link.

We are happy to continue our new inspired by Drug Hunter’s “Small Molecules of the Month” series!

Here are three molecules that were recently highlighted by Drug Hunter!

Last June, a group of researchers published a Perspective 'Fragment linking strategies for structure-based drug design'.

This exhaustive view describes usage of different approaches in fragment-based drug discovery (FBDD) - growing, linking, and merging - in design and synthesis of nearly 50 drugs and clinical candidates.

We at Chemspace offer 11 "In-Stock" Fragment Compound Sets!

Dear friends and colleagues!

Join Chemspace & Key Organics Webinar 'Key Organics Chemistry Solutions: Synthesis, building blocks, fragments and PROTACs', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on May 26th, 2021.

The Speaker is Dr. Steve Brough, Business Development Manager at Key Organics.

Register via the link now!

Trilacicilib (COSELA) received approval by the FDA in February 2021 as a drug to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage small cell lung cancer (SCLC).

Trilacicilib contains diazaspiro[5.5]undecan-3-one moiety in its backbone.

We have made a set of Building Blocks, which contain similar parts – the perfect start for your research!

Dear friends and colleagues!

Thanks to everyone for joining the  Chemspace & AnalytiCon Discovery Webinar 'Leveraging Natural Product based Chemical Spaces' yesterday!

For those who didn’t have a chance to connect, the recording is already available!

Join Chemspace & AnalytiCon Discovery Webinar 'Leveraging Natural Product based Chemical Spaces', which will take place at 5:00 PM (CET) / 8:00 AM (PST) TODAY, on May 11th, 2021.

The Speaker is Dr. Lars Ole Haustedt, Director Projects & Innovation at AnalytiCon Discovery.

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for April in case you have missed them!

ChemFaces is Chemspace reliable supplier which we are happy to recommend it to you preferably.

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Now they have more than 2000 products with good quality are provided with special offer up to 50% off.

Thiols are the Molecules of This Week! We at Chemspace always have new small molecules to power up your research. To browse the set please use this link.

Tivozanib (FOTIVDA) received approval by the FDA in March 2021 as a drug for the treatment of adult patients with relapsed or refractory advanced renal cell carcinoma (RCC).

Tivozanib contains 1,2-oxazole moiety in its backbone.

We have made a set of Building Blocks, which contain such parts with an amine group in different positions – the perfect start for your research!

Dear friends and colleagues!

Thanks to everyone for joining the  Chemspace & AnalytiCon Discovery Webinar 'Unique Chemical Space Covered by 3D Synthetic Chemistry: Beyond Ro5' yesterday!

For those who didn’t have a chance to connect, the recording is already available!

We are happy to introduce our new video series - Chemspace Tutorials.

Enjoy the Pilot!

https://youtu.be/hBrtZKlIgkk

Dear friends and colleagues!

Join Chemspace & AnalytiCon Discovery Webinar 'Unique Chemical Space Covered by 3D Synthetic Chemistry: Beyond Ro5', which will take place TOMORROW (April 29th, 2021) at 5:00 PM (CET) / 8:00 AM (PST).

The Speaker is Dr. Dietmar Wolf, Executive Vice President of AnalytiCon Discovery.

Register via the link now!

We are happy to continue our new inspired by Drug Hunter’s “Small Molecules of the Month” series!

Here are three molecules that were recently highlighted by Drug Hunter!

Last July, a group of researchers published a Review that highlighted several approaches addressed to overcome chemotype-specific resistance to inhibitors in anticancer treatment.

Targeting multiple binding pockets or allosteric binding sites and designing inhibitors with distinct binding modes are among such strategies. The two next approaches are targeted degradation using PROteolysis Targeting Chimeras (PROTACs) and cysteine-targeting covalent inhibitors.

We at Chemspace offer you sets with Covalent Fragments and Covalent Modifiers!

Dear friends and colleagues!

Join our second Chemspace & AnalytiCon Discovery Webinar 'Leveraging Natural Product-based Chemical Spaces', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on May 11th, 2021.
The Speaker is Dr. Lars Ole Haustedt, Director Projects & Innovation at AnalytiCon Discovery.

Register via the link now!

Dear friends and colleagues!

With a new version of DataWarrior you can get even more from the tool: search in Chemspace database!

Now the largest catalog available to search in DataWarrior!

https://youtu.be/0ypIiaDMQYk

Please visit chem-space.com if you want to source these compounds!

Trifunctional Aromatic Acids are the Molecules of This Week.

We at Chemspace always have new small molecules to power up your research.

To browse the set please use the link!

This March, Ponesimod (PONVORY) received approval by the FDA for the treatment of patients with relapsing forms of multiple sclerosis (MS). It is one of four sphingosine-1-phosphate (S1P) receptor modulators that bind selectively to S1P1 receptors, identified in having a pivotal role in the regulation of lymphocyte trafficking in MS.

Ponesimod contains 1,3-thiazolidine moiety in its backbone.

We have made a set of Building Blocks, which contain 1,3-thiazolidine parts – the perfect start for your research!

Dear friends and colleagues!

Join Chemspace & AnalytiCon Discovery Webinar 'Unique Chemical Space Covered by 3D Synthetic Chemistry: Beyond Ro5', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on April 29th, 2021.

The Speaker is Dr. Dietmar Wolf, Executive Vice President of AnalytiCon Discovery.

Register via the link now!

Dear friends and colleagues!

Thanks to everyone for joining the  Chemspace & CrystalsFirst Webinar 'How to optimize the fragment hit rate: take protein crystals first' yesterday!

For those who didn’t have a chance to connect, the recording is already available!

Dear friends and colleagues!

Join Chemspace & CrystalsFirst Webinar 'How to optimize the fragment hit rate: take protein crystals first', which will take place TOMORROW (April 13th, 2021) at 5:00 PM (CET) / 8:00 AM (PST).

Register via this link now!

Last year, a group of researchers from Google Research Applied Science and X-Chem, published an article that describes an effective approach for hit finding using Machine Learning (ML) based on DNA-Encoded Libraries (DEL). The authors demonstrate how ML could be applied to DEL selection data by identifying active molecules from large libraries of commercial and tangible compounds.

Chemspace inspires You to start new projects using DEL and we offer Blocks for creating DELs and Ready to use self-serve product from HitGen Inc. - OpenDEL®!

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for March in case you have missed them!