News and Events - Page 26

This April, a group of researchers posted an article called 'The powerful symbiosis between synthetic and medicinal chemistry'.
It combines synthetic chemistry and medicinal chemistry approaches - shows some novel synthetic bioisostere replacements for a number of functional groups.

Based on that, we at Chemspace prepared three great compound sets!

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for June in case you have missed them!

A new section is available on our website!
We are proud to announce our 'Services' section, where you can learn more about what Chemspace can do for you and your company.

Hetaryl Halide Nitriles are the Molecules of This Week!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

We did our best to create an informative series of posts on DNA-encoded libraries!

And today we are ending the campaign with «OpenDEL® - Billions in a Vial!».

It contains not only libraries for affinity selection, but a lot of other materials that will be nessesary for working with DEL. 

This March, an editorial called ‘What makes a good fragment in fragment-based drug discovery?’ was published.

The author covered the most up-to-date information on the principles, that define a good fragment and gave his expert opinion on the topic.

We at Chemspace already did all the work for you, so just check out our fragment sets!

Dear friends and colleagues!

Thanks to everyone for joining the Chemspace & MedChemExpress Webinar 'MedChemExpress: dedicated to enabling your success in biomedical research and drug discovery' yesterday! For those who didn’t have a chance to connect, the recording is already available!

Join Chemspace & Shanghai Institute of Materia Medica 'Intelligent DNA Encoded Library (iDEL) Technology for Small Molecule Drug Discovery', which will take place at 5:00 PM (CET) / 8:00 AM (PST) TOMORROW, on July 1st, 2021.

The last post of the DNA-encoded libraries (DELs) campaign is dedicated to novel hit selection strategies for DEL.

Three previous posts are here,  here, and here.

The third post of DNA-encoded libraries (DELs) campaign is about a tool for DEL creation - eDESIGNER.

Two previous posts are here and here.

The second post of DNA-encoded libraries (DELs) campaign is devoted to DNA-compatible chemical reactions based on this year's review.

The first post is here.

Enamine Ltd. a provider of drug discovery services empowered with the world’s largest collections of building blocks, fragments, and screening compounds announced today that it forms a strategic alliance with Chemspace, an online marketplace leader for small molecules, and will use the company as its exclusive aggregator platform to supply worldwide all its catalogue products starting from January 1, 2022.

Join Chemspace & Shanghai Institute of Materia Medica 'Intelligent DNA Encoded Library (iDEL) Technology for Small Molecule Drug Discovery', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on July 1st, 2021.

We are happy to announce our new campaign about DNA-encoded libraries (DELs).

The first post is an overview of this topic based on the paper published last January.

Heterocyclic Alkyl Halides are the Molecules of This Week!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

This May, a group of researchers published a miniperspective on the importance of isosteres for epigenetic drug discovery. They summed up the frequency of various post-translationally modified lysine bioisosteres found in different compound collections, discovering general trends.

We at Chemspace prepared 3 great sets of compounds based on oxazole, triazole and pyridone moieties!

Dear friends and colleagues!

Thanks to everyone for joining the Chemspace & MedChemExpress Webinar 'MedChemExpress: dedicated to enabling your success in biomedical research and drug discovery' yesterday!

For those who didn’t have a chance to connect, the recording is already available!

Dear friends and colleagues!

Join Chemspace & MedChemExpress Webinar 'MedChemExpress: dedicated to enabling your success in biomedical research and drug discovery', which will take place at 5:00 PM (CET)/8:00 AM (PST) TOMORROW, on June 17th, 2021.

The Speaker is Dr. Wei Li (Devid Li), Vice President at MedChemExpress.

Register via the link now!

We are happy to continue our new video series - Chemspace Tutorials.

Enjoy the Second Video!

We are happy to continue our new inspired by Drug Hunter’s “Small Molecules of the Month” series!

Here are two molecules that were recently highlighted by Drug Hunter!

Isocyanates are the Molecules of This Week!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

This May, a group of researchers published an article 'Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry'.

The paper describes synthesis of multiple DNA-encoded chemical libraries (DECL) for discovering covalent inhibitors.

At Chemspace, we offer In-Stock Covalent Modifiers library (>200K) from our Selected Screening set and also we provide Ready to use self-serve product from HitGen Inc. - OpenDEL®:  “OpenDEL® - Billions in A Vial!” - 1 Billion compound set.

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for May in case you have missed them!

This May, Infigratinib (TRUSELTIQ) received approval by the FDA for adults treatment of cholangiocarcinoma.

It is an ATP-competitive, FGFR1-3 tyrosine kinase inhibitor implicated in origin of FGFR-driven diseases.

Infigratinib contains dihalogen dimethoxy aniline moiety in its backbone.

We have made a set of Building Blocks, which contain similar parts – the perfect start for your research!

Dear friends and colleagues!

Thanks to everyone for joining the Chemspace & Key Organics Webinar 'Key Organics Chemistry Solutions: Synthesis, building blocks, fragments and PROTACs' yesterday!

For those who didn’t have a chance to connect, the recording is already available!