News and Events

A new version of Enamine REAL Space is now searchable through Chemspace!

You can access 20 Billion molecules here!

Many thanks to Enamine (https://www.enamine.net) for creating the largest synthetically accessible space and BioSolveIT (https://www.biosolveit.de) for developing an incredible search tool!

In 2019, a group of researchers discovered, that azaspiro[3.3]heptanes can act as replacements for morpholines, piperidines, and piperazines in a medicinal chemistry context.
The authors concluded that azaspiro[3.3]heptanes are most likely not suitable as bioisosteres, when not used as terminal groups.
We prepared a set of azaspiro[3.3]heptanes, that can become a great start for your research!

Dear friends and colleagues!

Thanks to everyone for joining the Chemspace & Vision Arcanum 'Towards a more natural way to draw chemical structures' yesterday!

For those who didn’t have a chance to connect, the recording is already available!

Dear friends and colleagues!

Join Chemspace & Vision Arcanum 'Towards a more natural way to draw chemical structures', which will take place at 5:00 PM (CET) / 8:00 AM (PST) TOMORROW, on July 22nd, 2021.

The Speaker is Dr. Vadim Fedorov, Co-founder at Vision Arcanum.

Register via the link now!

Hetaryl Amino Halides are the Molecules of This Week!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

Last September, a group of researchers published a review ‘Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold’.

Authors describe the list of compounds including this moiety, that appear in clinical trials and preclinical development.

We at Chemspace prepared a set of compounds based on pyrazolopyrimidine (1314 compounds) for your research!

Dear friends and colleagues!

Join Chemspace & Vision Arcanum Webinar 'Towards a more natural way to draw chemical structures', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on July 22nd, 2021.

The Speaker is Dr. Vadim Fedorov, Co-founder at Vision Arcanum.

Register via the link now!

We are happy to continue our series of posts, which are inspired by Drug Hunter’s “Small Molecules of the Month”!
Here are two molecules that were recently highlighted by Drug Hunter!

This April, a group of researchers posted an article called 'The powerful symbiosis between synthetic and medicinal chemistry'.
It combines synthetic chemistry and medicinal chemistry approaches - shows some novel synthetic bioisostere replacements for a number of functional groups.

Based on that, we at Chemspace prepared three great compound sets!

Meet Chemspace Monthly Digest! 

Here is a summary of all Chemspace news and highlights for June in case you have missed them!

A new section is available on our website!
We are proud to announce our 'Services' section, where you can learn more about what Chemspace can do for you and your company.

Hetaryl Halide Nitriles are the Molecules of This Week!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

We did our best to create an informative series of posts on DNA-encoded libraries!

And today we are ending the campaign with «OpenDEL® - Billions in a Vial!».

It contains not only libraries for affinity selection, but a lot of other materials that will be nessesary for working with DEL. 

This March, an editorial called ‘What makes a good fragment in fragment-based drug discovery?’ was published.

The author covered the most up-to-date information on the principles, that define a good fragment and gave his expert opinion on the topic.

We at Chemspace already did all the work for you, so just check out our fragment sets!

Dear friends and colleagues!

Thanks to everyone for joining the Chemspace & MedChemExpress Webinar 'MedChemExpress: dedicated to enabling your success in biomedical research and drug discovery' yesterday! For those who didn’t have a chance to connect, the recording is already available!

Join Chemspace & Shanghai Institute of Materia Medica 'Intelligent DNA Encoded Library (iDEL) Technology for Small Molecule Drug Discovery', which will take place at 5:00 PM (CET) / 8:00 AM (PST) TOMORROW, on July 1st, 2021.

The last post of the DNA-encoded libraries (DELs) campaign is dedicated to novel hit selection strategies for DEL.

Three previous posts are here,  here, and here.

The third post of DNA-encoded libraries (DELs) campaign is about a tool for DEL creation - eDESIGNER.

Two previous posts are here and here.

The second post of DNA-encoded libraries (DELs) campaign is devoted to DNA-compatible chemical reactions based on this year's review.

The first post is here.

Enamine Ltd. a provider of drug discovery services empowered with the world’s largest collections of building blocks, fragments, and screening compounds announced today that it forms a strategic alliance with Chemspace, an online marketplace leader for small molecules, and will use the company as its exclusive aggregator platform to supply worldwide all its catalogue products starting from January 1, 2022.

Join Chemspace & Shanghai Institute of Materia Medica 'Intelligent DNA Encoded Library (iDEL) Technology for Small Molecule Drug Discovery', which will take place at 5:00 PM (CET) / 8:00 AM (PST) on July 1st, 2021.

We are happy to announce our new campaign about DNA-encoded libraries (DELs).

The first post is an overview of this topic based on the paper published last January.

Heterocyclic Alkyl Halides are the Molecules of This Week!

We at Chemspace always have new small molecules to power up your research.

To browse the set please use this link.

This May, a group of researchers published a miniperspective on the importance of isosteres for epigenetic drug discovery. They summed up the frequency of various post-translationally modified lysine bioisosteres found in different compound collections, discovering general trends.

We at Chemspace prepared 3 great sets of compounds based on oxazole, triazole and pyridone moieties!

Dear friends and colleagues!

Thanks to everyone for joining the Chemspace & MedChemExpress Webinar 'MedChemExpress: dedicated to enabling your success in biomedical research and drug discovery' yesterday!

For those who didn’t have a chance to connect, the recording is already available!