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  • Chemspace Monthly Digest. November

    Meet Chemspace Monthly Digest! 

    Here is a summary of all Chemspace news and highlights for November in case you have missed them!

  • Molecules of This Month are Sulfonamide Amines!

    Sulfonamide Amines are the Molecules of the Month!

    We at Chemspace always have new small molecules to power up your research.

    To browse the set please use this link.

  • Three Lead-Like Diversity Sets are now out on the website!

    Three Lead-Like Compound Libraries are now out on the website! Each set is comprised of 10 thousand diversified molecules and is available for download.

  • New Publications section is now available on the website!

    Today we are proud to show you a new section on our website – Publications. Here you can find out more about publications co-authored by Chemspace and publications featuring our company.

  • Macrocycles in DNA-encoded libraries

    DNA-encoded libraries can be utilized as a great tool for developing and screening macrocycles in Drug Discovery. Check out the article and the offers we prepared for you here!

  • Imidazo[1,2-b]pyridazines in medicinal chemistry

    George Spacey continues to work on our weekend series and today he is ready to present you an amazing review on imidazo[1,2-b]pyridazines and their biological activity. The traditional compound set is also waiting for you!

  • Building Blocks for Analogs of Viloxazine

    This April, Viloxazine received approval by the FDA  as an oral drug for the treatment of attention deficit hyperactivity disorder (ADHD) in children.

    It acts as a selective norepinephrine reuptake inhibitor (NRI).

    Viloxazine contains morpholine moiety in its backbone.

    We have made a set of Building Blocks, which contain such parts – the perfect start for your research!

     

  • NEW Chemspace Website tutorials are live!

    Three new Chemspace tutorial videos are already available on our YouTube channel! We try our best to guide you through the most important steps of interaction with our website.

  • Sulfoximines in medicinal chemistry

    Interest in sulfoximine chemistry has been greatly increased recently, and todays’ article is all about this topic. Chemspace also offers a great sulfoximine-containing compound set!

  • Chemspace is proud to present Protein Kinases Targeted Libraries!

    Chemspace is proud to present a new product – Protein Kinases Targeted Libraries! General and Allosteric compound libraries are waiting for your attention here!

  • Chemspace & Dr. Vsevolod Katritch Webinar. Recording

    Dear friends and colleagues!

     

    Thanks to everyone for joining the Chemspace Webinar with Dr. Vsevolod Katritch - 'Fast Structure-Based Virtual Screening in Readily Available Chemical Space of >10 Billion Compounds'!

    For those who didn’t have a chance to connect, the recording is already available!

  • Bioactive pyrrole-based compounds with target selectivity

    Our todays’ review is focused on pyrrole and its hetero-fused derivatives with anticancer, antimicrobial, and antiviral activities.

    A pyrrole-based compound set is waiting for you!
     

  • Meet Chemspace mascots – George and Alex Spacey!

    Meet Chemspace mascots! They will help us to guide you through the latest Chemspace news and plans. And we hope you`ll love them too!

  • Chemspace Monthly Digest. October

    Meet Chemspace Monthly Digest! 

    Here is a summary of all Chemspace news and highlights for October in case you have missed them!

  • Meet Chemspace at CPhI Worldwide 2021!

    We are looking forward to catching up with you in-person at CPhI Worldwide!
    See up!

  • Molecules of This Month are Halogenated Benzaldehydes!

    Halogenated Benzaldehydes are the Molecules of the Month!

    We at Chemspace always have new small molecules to power up your research.

    To browse the set please use this link.

  • Chemspace provides computational chemistry services!

    If you haven`t found your target in our library, our computational chemistry services team is ready to help you to create a custom one! For the full list of services write at enquiry@chem-space.com.

  • Building Blocks for Analogs of Atogepant

    This September, Atogepant received approval by the FDA as a drug for the treatment of episodic migraine.

    It is an oral calcitonin gene-related peptide (CGRP) receptor antagonist.

    Atogepant contains aminopiperidinone moiety in its backbone.

    We have made a set of Building Blocks, which contain such parts – the perfect start for your research!

  • Chemspace reveals GPCRs Targeted Library!

    Today we are proud to reveal GPCRs Targeted Library – an amazing new product, prepared by our computational chemistry services team.

    590K+ compounds against 192 targets are waiting for you here!

  • Cryo-EM as a promising approach for GPCR Drug Discovery

    The article we want to share today shows, that now it is possible to obtain high-quality 3D reconstructions by cryo-EM without the need for a stabilizing nanobody and with reduced cost.

  • Join Chemspace & Dr. Vsevolod Katritch Webinar Tomorrow!

    Dear friends and colleagues!

    Join the Chemspace Webinar 'Fast Structure-Based Virtual Screening in Readily Available Chemical Space of >10 Billion Compounds', which will take place at 5:00 PM (CET) / 8:00 AM (PST) TOMORROW, on October 21st, 2021.


    The Speaker is Dr. Vsevolod Katritch, Assoc. Professor at the University of Southern California.

    Register now via the link!

  • Impact of GPCR Structures on Drug Discovery

    We are continuing our series of posts on GPCRs!

    Determination of GPCRs structures is highly important for classification and SBDD on these targets. This thought is the key point of today’s highlighted article.

  • Chemspace starts GPCR information week!

    We are starting our GPCR information week with a nice review on GPCRomics – its approaches, gaps in knowledge, and future directions.

  • Antiproliferative activity of thiazole and oxazole derivatives

    This year a group of scientists summarized the biological activity of thiazole and oxazole derivatives. We thought this is a great idea to provide you with two compound sets based on it!

  • Chemspace Catalog is already updated!

    Chemspace Catalog is already updated!
    This means that now you are able to search in more than 4.3 Billion molecules!

    So don’t waste your time and go check out the new compound choices that might become the perfect fit for your research!

    https://chem-space.com/search

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