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  • Bioisosteres of an ortho-Substituted Benzene

    Discover Chemspace ortho-Substituted Benzene Bioisosteres – a library of 120 in-stock compounds featuring saturated bicyclic scaffolds that can potentially mimic 1,2-disubstituted phenyl ring properties. Replacement with these moieties represents a promising tactic leading to enhanced water solubility and decreased lipophilicity with retained biological activity.

  • Shopping season start! Check out our General Pre-Plated Library!

    It's shopping season and we have got just what you need to speed up your research projects!

    Check out our General Pre-Plated Library – your ultimate solution for lightning-fast early-stage screenings!

  • Meet new Chemspace CEO – Dr. Olga Tarkhanova!

    Please welcome our new CEO – Olga Tarkhanova, PhD!

  • Analogs to New Biological Tool Compounds - 28

    Here comes a new post in our series inspired by Drug Hunter’s “Molecules of the Month”!
    Today it is DNL343 - an oral eIF2B activator in Phase II/III for the treatment of amyotrophic lateral sclerosis (ALS).

  • Chemspace Monthly Digest. September 2023

    Missed the Chemspace news and highlights for September?

    Here is a comprehensive summary of all our posts for this summer month!

  • Building Blocks for Analogs of Momelotinib

    This month Momelotinib (OJJAARA©) was approved by FDA as a drug for the treatment of myelofibrosis in adults with anemia.

    It contains a morpholine ring, and we offer bioisosteres of such moiety that can improve PK properties of compounds!

  • Announcement about possible delays from Chinese vendors

    We would like to let you know about possible delays from Chinese vendors that might be in place for the next week.
    We sincerely apologize for any inconvenience!

  • Meet Weekend Article about a New Method SILVR!

    The new weekend article is here! Follow the link and read about a new method for conditioning an existing diffusion-based equivariant generative model without retraining!

  • Chemspace & Arrayjet Webinar. Recording

    Thanks to everyone for joining the Chemspace & Arrayjet Webinar ’Small Molecule Microarrays for Drug Discovery’ presented by  Dr. Adam Buckle, Chief Scientific Officer at Arrayjet. Hosted by Oleksii Gavrylenko, our Chief Operating Officer.

    For those who didn’t have a chance to connect, the recording is already available on the Chemspace YouTube channel!

  • Join the Chemspace & Arrayjet Webinar TOMORROW!

    Join the Chemspace & Arrayjet Webinar ’Small Molecule Microarrays for Drug Discovery’, which will take place TOMORROW, September 21st at 4 PM (CET) | 7 AM (PST)!

    The speaker is Dr. Adam Buckle, Chief Scientific Officer at Arrayjet. Hosted by Oleksii Gavrylenko, our Chief Operating Officer!

    Register via the link now!

  • Biologics for Research – Glucagon-like Peptide-1 Receptor

    We continue our series of posts in the Biologics campaign! Today, we focus on the glucagon-like peptide-1 receptor (GLP-1R).

    At Chemspace, we offer various GLP-1R-related proteins, peptides, RNAs, highly selective antibodies, and kits!

  • Bioisosteres of a meta-Substituted Benzene

    Discover Chemspace meta-substituted benzene bioisosteres – a library of 260 in-stock compounds that can mimic phenyl ring properties and potentially enhance physicochemical and pharmacokinetic characteristics of molecules in the drug development process.

  • General Pre-Plated Library Update! Now more than 623K!

    Latest news! We have a library update, now more than 623 thousand compounds in one place – a great starting point for your research projects! Check them out on the product page!

  • Explore Freedom Space 3.0 and Enamine REAL at once!

    Great update! Now you can explore Enamine REAL and Freedom Space 3.0 simultaneously!

    Just follow the link and start searching!

  • Meet CS Team – Account Manager Tetiana Herman!

    Today we would like you to meet our Account Manager – Tetiana Herman. Follow the link to get to know her better!

  • Join the Chemspace & Arrayjet Webinar!

    Join the Chemspace & Arrayjet Webinar ’Small Molecule Microarrays for Drug Discovery’, which will take place at 4 pm | 7 am (PST) on September 21st, 2023.

    The speaker is Dr. Adam Buckle, Chief Scientific Officer at Arrayjet. Hosted by Oleksii Gavrylenko, our Chief Operating Officer!

    Register via the link now!

  • Join the Chemspace Webinar Tomorrow!

    Join our webinar dedicated to Machine Learning approaches for the creation and exploration of chemical spaces, which will take place TOMORROW, September 7th!

  • Analogs to New Biological Tool Compounds - 27

    Here comes a new post in our series inspired by Drug Hunter’s “Molecules of the Month”!
    Today it is JNJ-54175446 - an oral P2X7R antagonist in Phase II for major depressive disorder (MDD).

  • Compound Sourcing with Chemspace!

    We at Chemspace provide a one-stop shop for your compound purchasing campaign, and we would be happy to assist with it!

  • Join the Chemspace Webinar!

    Join our webinar dedicated to Machine Learning approaches for the creation and exploration of chemical spaces!

  • Chemspace at EFMC-ASMC 2023 in Zagreb!

    We are excited to announce that Rita Gaidar, our Director of Business Development will be attending EFMC-ASMC 2023 in Zagreb, Croatia.
    She will present the poster dedicated to a new AI-driven approach to hit identification (poster session №1, P079).

  • Small-molecule discovery through DNA-encoded libraries

    DNA-encoded library (DEL) is a powerful and broadly applicable small-molecule discovery method that has been increasingly applied to the discovery of chemical probes and novel clinical candidates.

  • Dr. Olga Tarkhanova at ACS Fall 2023 in San Francisco

    Dr. Olga Tarkhanova at ACS Fall 2023 in San Francisco presenting on Machine Learning Approaches for the Creation and Exploration of Chemical Spaces.
     

  • Stay curious, stay informed: Subscribe to Chemspace Newsletter!

    Introducing our newsletter - your gateway to the latest updates, news, and ideas from the world of chemistry, biology, and Chemspace!

  • Bioisosteres of a tert-Butyl Group

    Introducing our new set of Building Blocks – the most prominent bioisosteres of the tert-butyl group for marketed drugs and drug candidates! We offer 160 in-stock compounds that can mimic such moiety!

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